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This study demonstrated that WRF is common and occurs often in a real world ADHF patient population utilizing UF as a rescue decongestive and volume removal strategy after failure of standard medical decongestive therapies. Treatment with Aldosterone antagonists, preexisting low heart rate, and increased LV filling pressure as assessed by echocardiogram at hospital admission can identify [http://en.wikipedia.org/wiki/PDGFRB PDGFRB] patients at increased risk for WRF. Mortality was highest, 75% at 1 year, for patients who presented with GFR [http://www.selleckchem.com/products/chir-99021-ct99021-hcl.html CT99021 ic50] for UF. None. ""In the article ��Effect of Cardiac Resynchronization Therapy on Left Ventricular Diastolic Function: Implications for Clinical Outcome�� by Doltra et?al (J Card Fail 2013;19:795-801), a number of standard deviations were cited incorrectly throughout the article. Because these errors appear throughout the article, the full and corrected version of the article has been posted online along with this erratum. Clinical Trial: Effect of Cardiac Resynchronization Therapy on Left Ventricular Diastolic Function: Implications for Clinical Outcome Background: The definition of response to cardiac resynchronization therapy (CRT) remains controversial, with variable rates of response depending on the criteria used. Our aim was to analyze the impact of CRT on diastolic function in different degrees of response, particularly in patients with positive clinical but no echocardiographic response. Methods and Results: In 250 CRT patients clinical evaluation and echocardiography were performed before and after CRT. Absolute response to CRT was defined as a reduction in left ventricular (LV) end-systolic volume of ��15% at 1-year follow-up. Additionally, patients were classified into 4 subgroups according to their [http://www.selleckchem.com/products/PLX-4032.html this website] amount of response: extensive reverse remodeling (RR), slight RR, clinical response without RR, and neither clinical response nor RR. An improvement in estimates of LV filling pressure and a decrease in left atrial dimensions were observed only in responders to CRT. Patients with clinical but no echocardiographic response had significant improvement in E-wave and deceleration time and nonsignificant improvement in other parameters. Conclusions: LV diastolic function improves with CRT. Clinical responders without echocardiographic response show improvement in parameters of diastolic function.