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MI, measured as the intensity of covariation among head traits, was assessed using data from three-dimensional head landmark coordinates taken on 176 individuals. Individuals carrying the derived allele of the rs4647905:G>C polymorphism present significantly greater levels of head MI, especially in facial structures and on the shape space where the modular portion of the covariation is explicitly removed. Since FGFR genes present nonconservative and tissue-specific splicing sites, they may have some effect on protein structure and performance likely involved in developmental processes responsible for the magnitude and pattern of MI in the human head. Am. J. Hum. Biol. 26:164�C175, 2014. ? 2013 Wiley Periodicals, Inc. ""4416"	"Studies of the placenta in pregnancies complicated by pre-eclampsia have led to the suggestion that tissue along [http://www.selleckchem.com/products/17-AAG(Geldanamycin).html 17-AAG ic50] the length and breadth of its surface has different functions. A recent study in Saudi Arabia showed that the body size of newborn babies was related to the breadth of the surface at birth but not to its length. We have now examined whether the association between placental breadth and body size reflects large size of the baby from an early stage of gestation or rapid growth between early and late gestation. We studied 230 women who gave birth to singleton babies in King Khalid Hospital, Riyadh, Saudi Arabia. In total, 176 had ultrasound measurements both before 28 weeks and at 28 weeks or later, which we define as early and late gestation. We used these to calculate growth velocities between early and late gestation, which [http://www.selleckchem.com/products/lgk-974.html LGK974] we expressed as the change in standard deviation scores over a 10-week period. The breadth of the placental surface was correlated with fetal growth velocity. The correlation coefficients were 0.24 (P?=?0.002) for the head circumference, 0.24 (P?=?0.001) for the biparietal diameter and 0.34 (P?[http://en.wikipedia.org/wiki/Ebastine Ebastine] of the surface was not related to fetal growth velocity. Tissue along the breadth of the placental surface may be more important than tissue along the length in the transfer of nutrients from mother to baby. This may be part of a wider phenomenon of regional differences in function across the placental surface. Am. J. Hum. Biol. 25:534�C537, 2013. ? 2013 Wiley Periodicals, Inc. ""4417"	"Despite research and clinical significance, limited information is available on the relations between skeletal muscle (SM) and age in adults, specifically among Hispanics, African Americans (AA), and Asians. The aim was to investigate possible sex and ethnic SM differences in adults over an age range of 60 years. Subjects were 468 male and 1280 female adults (��18 years). SM was estimated based on DXA-measured appendicular lean-soft tissue using a previously reported prediction equation.