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4.1. Data Analysis Wilcoxon signed-rank tests using SPSS 22.0 were performed to evaluate whether participants significantly improved on UPDRS score and Hoehn and Yahr stage after their Operation House Call participation. Demographic data (such as participant [http://www.selleckchem.com/products/GDC-0449.html www.selleckchem.com/products/GDC-0449.html] age and distance from center) was reported using mean and standard deviation. 5. Results There were a total of seven patients who had home visits that were initiated from January 2011 to January 2014. One patient was diagnosed with a psychogenic movement disorder and was provided with counseling therapy and later was discharged. The sixth patient (see Table 1) was able to obtain medical insurance after 4 visits (one year of OHC) and later was successfully implanted with a deep brain stimulator and discharged from the program with follow-up in the clinic setting. Five patients remain active in OHC. Table 1 Summary of Operation [https://en.wikipedia.org/wiki/Quinapyramine Quinapyramine] House Call demographics, UPDRS, H & Y scores, and medications before and one year after completion and summery of mood and hospitalization data. There were 3 males and 3 females in the cohort with PD, and the mean age was 64 �� 8.2 (SD). Five patients were initially enrolled due to inability to obtain insurance, and one patient was unable to afford the cost of transportation. All of the patients who could not afford insurance cited a hardship in affording the transportation necessary to see a medical specialist. The cohort reported latency to being evaluated by a neurologist of 1.4 years (mean) (range [http://www.selleckchem.com/products/MS-275.html MS 275] .025 to 2 years). The reasons included lack of access to a local neurologist (n = 3) and financial burden (n = 6). The medication regimens prior to enrollment in OHC are summarized in Table 1. Briefly, n = 3 patients were not on PD medical therapy and n = 2 patients were prescribed carbidopa/levodopa by a local general practitioner but had not initiated the medication. The reason cited by both patients was a concern about the accuracy of the diagnosis. One patient started amantadine 6 months prior to OHC. Following OHC n = 6 patients were prescribed carbidopa/levodopa; n = 1 patient was prescribed citalopram for depression; and n = 1 patient was prescribed escitalopram also for the indication of depression. CGIS scores were much improved (a rating of 2/7) for all six patients. A clinical coordinator checked in regularly with patients by phone to ensure adherence to the new medication regimens. Two patients were identified with clinically significant depression without suicidal ideation, and both were treated without the need for hospitalization. Each patient had a mean of 3.67 �� 0.52 (SD) home visits a year (Table 1). Using SPSS 22.0, a Wilcoxon signed-rank test was run to examine whether the UPDRS motor score significantly differed before and after Operation House Call participation. Results revealed significant improvement, Z = ?2.00, P