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3% (n?=?5) Type C fractures, and 3.2% (n?=?3) Type B fractures. 29.8% (n?=?28) were superior burst-split fractures (Type A 3.2.1), 28.7% (n?=?27) Type A 1.2.1, 11.7% (n?=?11) Type A 3.1.1, and 10.6% (n?=?10) Type A 1.1 fractures. Other subtypes of the Magerl classification were rare ([http://www.selleckchem.com/products/Erlotinib-Hydrochloride.html Erlotinib ic50] Eight patients (4.4%) sustained spino-pelvic dissociation fractures. All of them were paragliders. In these patients, sacral fractures were classified according to Roy-Camille as Type 1 and 2 in two cases each, and as [http://en.wikipedia.org/wiki/MCF2L MCF2L] Type 3 in four cases (Fig. 1). Five of these patients were treated with posterior decompression and triangular lumbopelvic osteosynthesis,21?and?22 and the other three with trans-iliacal screws only.23?and?24 One patient with spino-pelvic dissociation showed no neurological symptoms (Roy-Camille Type 1). In seven patients, we observed neurological impairment with complete involvement of all nerve roots below L5. All but one patient showed some slow improvement over time, but neurological impairment persisted. Two patients suffered from permanent bladder and bowel dysfunction. In all patients, complete bone healing was achieved within 6?months, [http://www.selleckchem.com/products/AP24534.html selleck screening library] and no infections were noted (Table 3; Fig. 3?and?Fig. 4). During the study period from 2000 to 2009, 1745 general trauma patients underwent surgery of the spine or pelvis at our Level I trauma centre. Of these, 12 had suffered spino-pelvic dissociation fractures (Fig. 5). The fractures were classified as Roy-Camille Type 1 in seven, Type 2 in four, and Type 3 in one patient. Five of these presented with neurological impairment. Multivariate analysis adjusted for age and gender showed a 21-fold higher OR (OR 21.04, 95% CI 7.83�C56.57, p?