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3%) patients completed 10?years follow-up and only 55 (5.7%) patients defaulted follow-up. Of these, 26 (2.7%) had died with 19 (73%) deaths from non-CVD causes. Figure?1 Flow chart of patients included in the analysis. Inclusion criteria All adult patients 30?years and older, without any cardiovascular events and with documented blood pressure (BP) readings whether they were on or not on treatment, total cholesterol, high-density lipoprotein (HDL) cholesterol, smoking status, and presence or absence of diabetes mellitus (DM) were eligible for this study. These parameters were needed to compute each individual's general CVD risk level. Design This sample was randomly selected using a computer-generated number based on the patient's unique registration number with the clinic. All patient records were in paper form. Data collection We extracted the patients�� sociodemographic data and clinical [http://www.selleckchem.com/products/ag-1478-tyrphostin-ag-1478.html Tyrphostin AG-1478 research buy] information based on the first entry in 1998 from [https://en.wikipedia.org/wiki/CAPNS1 CAPNS1] their records manually, according to a predetermined proforma (clinical report form). Use of hypoglycaemic and lipid-lowering agents were also captured. Using age, SBP (systolic BP; treated or not treated) total cholesterol, HDL cholesterol levels, smoking and diabetes status, we computed each individual's general CVD risk score. CVD events, namely, fatal and non-fatal CHD, fatal and non-fatal strokes, heart failure and peripheral artery disease were also captured from the records. For those who did not complete their subsequent 10-year follow-up at our clinic (n=24), we traced and examined the case records from the main hospital to determine their CVD outcome. For those patients who did not complete their follow-up in our clinic, we contacted them individually (n=31) to ascertain their CVD status and for any events fatal or non-fatal. Each CVD event was counted as one event in individuals who had more than one event during the 10-year follow-up. We further categorised the 10-year CVD risk as low (20% CVD risk.20 Blood pressure (BP) was measured by our attending doctor using a mercury sphygmomanometer as part of the daily routine clinical practice. Diagnosis of hypertension was made in accordance with standard recommendations.7 Target control BP is defined as BP[http://www.selleckchem.com/products/XL880(GSK1363089,EXEL-2880).html Selleck GSK1363089] without DM and