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0%) disorders of the conjunctiva. Children with the highest proportions of ophthalmologic disease included those with mycoplasma pneumonia (26.7%), herpes simplex virus (15.6%), upper respiratory infection (13.9%), and lower respiratory infection (13.7%). Individuals with EM, SJS, or TEN and ophthalmologic disease were more likely than those without ophthalmologic disease to receive intensive care unit care (28.3% vs 17.0%, p?=?0.03) and to be admitted to a children's hospital (63.3% vs 48.8%, p?=?0.03). Ophthalmologic disease was also [http://www.selleckchem.com/products/BAY-73-4506.html Selleck Regorafenib] associated with a significantly longer median length of stay (6.0?days, interquartile range [IQR] 3�C9?days vs 3.0?days, IQR 2�C6?days, p?[https://en.wikipedia.org/wiki/Floctafenine Floctafenine] morbidity and minimize long-term sequellae. ""Abstract:? An 11-year-old girl with a history of diabetes mellitus type I and celiac disease presented with multiple, depressed patches of purple-brown skin on the right lower extremity and central back, with histopathologic features of early morphea. Though morphea may coexist with other autoimmune diseases, its presentation with both diabetes mellitus type I and celiac disease has not yet been described. ""This chapter contains [http://www.selleckchem.com/products/torin-1.html find more] sections titled: Introduction Orthopox infection in humans Human parapox infections References ""This chapter contains sections titled: References ""In children the rare autoimmune skin diseases pemphigus, pemphigoid and epidermolysis bullosa acquisita and their variants may occur. Unfortunately, delay in diagnosis occurs frequently. In these dermatoses, antibodies are formed against one of the antigens involved in cell adhesion within either intercellular epidermal cells or the epidermal basement membrane zone. This antibody formation eventually leads to blistering of the skin and/or the stratified epithelium of mucous membranes. In children with these diseases, systemic treatment with prednisone is often necessary to induce remission of the disease; in serious cases, the addition of azathioprine, cyclophosphamide, intravenous immunoglobulines or rituximab may be needed. In some cases, topical corticosteroids or oral dapsone suffice. In most cases the prognosis quoad vitam is good, but the general prognosis is variable and sometimes lifelong treatment may be necessary.