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36; p  in the SL patient (t [http://www.selleckchem.com/products/gsk1120212-jtp-74057.html selleck products] conditions [http://www.selleckchem.com/products/Bortezomib.html learn more] in SL (cool and warmth sensations). In sum, when compared with both control groups, the IL patient showed no impairments in taste or thermal-pain sensation, which confirms our hypothesis, but a lower smell performance than healthy controls, which did not survive covariation. Conversely, when compared with healthy controls, the SL patient exhibited impaired smell identification, and diminished sensitivity to cool and warm sensations as well as to global thermal-pain sensation. Such impairments remained in the comparison with the brain-damaged controls, also confirming the hypothesis. Assessment of internal stream of interoception Heartbeat detection task (HBD) Compared with healthy controls, the IL patient (Figure ?(Figure3)3) showed impaired cardiac interoception (t  performance was spared in both the interoceptive and the motor control (see Table ?Table2)2) conditions. Even after covariation for HBD performance, the IL patient had significantly lower scores (t [https://en.wikipedia.org/wiki/Lazabemide lazabemide] whereas the SL patient performed similarly (see Table ?Table4)4) to controls. Figure 3 Internal stream: HBD task. Results of the accuracy in the HBD task. Left side of the panel shows the motor control condition, where no differences where observed given that all participants performed the task accurately. The right side of the panel shows ... The patients' differential patterns were replicated following comparison with the brain-damaged group. The IL patient exhibited impairments in the interoceptive (t