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65; p?[http://en.wikipedia.org/wiki/Histamine_H2_receptor Histamine H2 receptor] interaction (F(1, 68)?=?8.10; p?=?0.006), indicating significantly impaired performance in patients in the incongruent condition. The patients showed 98.5% (SD?=?3.4%) correct responses in the congruent and 84.6% (SD?=?12.2%) correct responses in the incongruent condition. The control subjects showed 99.2% (SD?=?1.9%) correct responses in the congruent and 93.5% (SD?=?10.4%) correct responses in the incongruent condition. There was a significant difference in performance accuracy between groups for the incongruent (p?[http://www.selleck.co.jp/products/DAPT-GSI-IX.html DAPT price] Mean endogenous parameters for both groups are displayed in Table?2. As illustrated in Fig.?3, the patients showed lower endogenous parameters in the projections from the dACC to the left (p?=?0.007) and right thalamus (p?=?0.003), and stronger connectivity from the right DLPFC to the right thalamus (p?=?0.003). All comparisons survived FDR correction for multiple comparisons. On the uncorrected level patients showed a lower connectivity between the dACC and the right DLPFC (p?[http://www.selleck.co.jp/products/Gefitinib.html Gefitinib mouse] white matter voxels located bilaterally in the MD. The second cluster consisted of voxels lying in the right frontal lobe in close proximity to the cingulum bundle. On the left side, the patients showed decreased left frontal WM volume near BA 8. No significant differences were detected in the opposite contrast. In patients with schizophrenia, a significant negative correlation between decreased endogenous parameter of the connectivity between dACC and left (r?=???0.38, p?=?0.027) as well as right MD (r?=???0.42, p?=?0.014) and the Stroop interference time was detected, indicating increased time demand to resolve the response conflict in the presence of decreased intrinsic cingulo-thalamic effective connectivity.