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001) for patients who were readmitted. In addition, patients who were readmitted were more likely to be initially discharged to an environment with some level of medical follow up �C such as home health assistance, [https://en.wikipedia.org/wiki/ALPI ALPI] skilled nursing, rehabilitation centre, law enforcement, etc. (51% vs. 44%, OR 1.3, p?=?0.002). Readmitted patients had significantly higher rates of comorbidities at their initial hospitalization (see Table 2). Higher rates of COPD (10% vs. 7%, p?=?0.01), DM (15% vs. 9%, p?[http://www.selleckchem.com/products/AG-014699.html PARP inhibitor] (4% vs. 1%, [http://www.selleckchem.com/products/otx015.html OTX015 nmr] infections), noninfectious complications of the injury or hospitalization, pain control, complications of prior medical conditions, complications of nonoperative therapy, ongoing treatment of the injury (i.e. further surgical procedures), failure of discharge planning or communication (��Systems failures�� in Table 5), and reasons unrelated to the injury. Various risk factors were significantly associated with the specific reason for readmission on multivariable analysis. Our report is one of the first large-scale studies investigating the rates of hospital readmission in the trauma population, along with a description of associated risk factors. Overall, the rate of early hospital readmission for trauma patients in our urban, academic, tertiary-referral centre was low (4.3%). Other studies that have described the readmission rate for injured patients have generally grouped them by injury type, i.e. hip fracture, spinal cord injury, etc.