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Animal bites are an important health-care problem and a common cause of trauma to the face and hands in children throughout the world.36 The impact of fatal and non-fatal animal bite wounds could be considered as a significant cost factor.1, 19, 37?and?38 Those injuries are not similar by characteristics of animals involved and types of injuries sustained.37?and?39 Despite the existence of different fauna, dogs and cats can be considered to be the main source of bite wounds in children.37, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49?and?50 According to the literature, we have to estimate a number of up to 50% of unmentioned bite wounds, a fact influencing the interpretation of existing findings [http://www.selleckchem.com/products/PF-2341066.html Crizotinib in vitro] and treatment modalities.1, 2?and?4 After reviewing the recent literature, data reflect dogs as the main source (80�C90%) followed by cats (5�C15%) for animal-related bite wounds.1?and?14 Cat bites, less invasive than dog bites, have a more than double infection rate, due to the fact of punctured wounds caused by small tusks.1?and?14 After a close look at the paediatric subgroup of bite wounds, some interesting facts could be extracted. Children under 5 years are the highest risk group in our population, but no male predominance as reported in the literature was observed7, 16, 36?and?51 (Table 5). Those numbers are interpreted by the fact that children in this group are almost unable to recognise the emotional behaviour of animals and that their face and hands are exposed on the same [http://www.selleckchem.com/products/INCB18424.html selleck products] level as the dogs jaw.36?and?52 Our data also outline a gender-related prevalence as reported [https://en.wikipedia.org/wiki/Meprobamate meprobamate] in the literature, dog bites are more common in men (53.2%), by contrast, cat bites have a higher occurrence in women (69.4%) (p?