Перегляд вихідного коду сторінки Indicators On The FMO5 You Should Know

Across the study period, there was significant variation in the proportion of neonates with an arterial lactate value greater than 6.7?mmol/L; only occurring when comparing the first versus the last period. [http://en.wikipedia.org/wiki/FMO5 FMO5] Unadjusted logistic regression analysis noted a significant increase in the proportion of neonates with arterial lactate values greater than 6.1?mmol/L and 6.7?mmol/L when comparing epoch one with epoch four (Table?3). After adjusting for demographic, obstetric and intrapartum covariates, the changes were no longer statistically significant (Table?3). At the metropolitan secondary level obstetric unit (Unit C), 84.5% (n?=2812) of the neonates had at least one cord blood gas result recorded, with 73.6% (n?=?2451) having a set of results for both the umbilical artery and umbilical vein. Over the two years of evaluation, there was no significant difference in the proportion of neonates with paired validated umbilical cord blood gas values (P?=?0.429). Univariate comparison of mean umbilical cord blood gas values revealed significant variation in arterial pO2 (P?=?0.006) values around a point with no pattern of increase or decrease over the two-year study period (Table?2). These changes remained significant after adjusting for maternal, neonatal and obstetric covariates. In the metropolitan secondary obstetric centre, there was a 21% reduction in arterial [http://www.selleckchem.com/products/Bafilomycin-A1.html Bafilomycin A1] pH[http://www.selleckchem.com/products/pf-06463922.html PF-06463922] significant reduction in the proportion of neonates with measures of acidosis outside the predefined thresholds when the first time epoch was compared with each of the subsequent three (Table?3). Evaluation of the one and five minute Apgar scores at Unit B over the study period revealed no significant variation in the proportion of neonates with Apgar scores less than four or less than seven. Unadjusted and adjusted logistic regression analyses noted no significant differences between the first and any of the following time periods. At Unit C, there were no significant changes in one-, five- or ten-minute Apgar scores over the study period in univariate and multivariable logistic regression. No Apgar scores were available for analysis at Unit A. This study represents the first evaluation of which we are aware of the impact of introducing cord blood gas analyses into primary and secondary obstetric units in metropolitan and regional centres. The data presented demonstrate a 61% reduction in arterial lactate levels greater than the population based 95th percentile and a 69% reduction in arterial lactate levels greater than the 99th percentile. The reduction in the rate of metabolic acidaemia in the primary obstetric centre is of similar magnitude to that seen when UCBGA was introduced into a tertiary obstetric centre with more than 6000 deliveries per year.