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The mean age of this cohort was 36.7, and self-reported race was 32% white, 27% black, 22% Hispanic, and 19% multiple race, Asians, American Indians, or others. Table 1 compares demographic and clinical information in groups with and without desire for future pregnancy. Women desiring pregnancy were younger (32.6 versus 39.9, p [http://www.selleckchem.com/products/azd9291.html AZD9291 research buy] communication. Most women in the study were sexually active (desire 64% versus no desire 74%, p = 0.38). There were high but similar rates of serodiscordant partnerships among sexually active women (desire 69% versus no desire 71%, p = 0.77) with both groups reporting that concern of infecting partner with HIV affected pregnancy plans (desire 51% versus no desire 33%, p = 0.12). Despite these concerns, only 20% of women with reproductive intent were referred to a reproductive specialist to discuss alternative methods of pregnancy. Table 2 Sexual history, fertility desires, and provider communication for women [http://www.selleckchem.com/products/carfilzomib-pr-171.html Selleckchem PR 171] with HIV of reproductive age. Nondisclosure of HIV status to any partner in the prior year was relatively high (no desire 29% [n = 14] versus desire 18% [n = 7], p = 0.53). Condom use rates and type of birth control in women with or without reproductive desire did not differ (Table 2). [http://en.wikipedia.org/wiki/YES1 YES1] Of 44 women with desire for future pregnancy, 84% thought they would have a future child and 10 women (23%) currently reported condomless sex with the goal of pregnancy. Interestingly, two women (4%) who did not report desire for a future pregnancy reported that they thought they would have a future child. Just under half of HIV-infected women reported that their HIV diagnosis impacted their pregnancy plans regardless of their desire for future pregnancy (45% versus 45%, p = 1). There was no difference (p = 0.71) in the knowledge-based MTCT question: ��If you were to become pregnant, what is the probability that your child will contract HIV with proper medication and medical guidance?�� Provider rates of discussion were the highest for condom use (desire 96% versus no desire 93%, p = 0.69) followed by contraception use (desire 64% and no desire 77%, p = 0.19) and the lowest in assessing desire for pregnancy (desire 41% versus no desire 35%, p = 0.68). Women desiring pregnancy were more likely to initiate a discussion with providers regarding pregnancy intent (42% versus 5%, p �� 0.0001).