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The echocardiographic assessments of acute PE patients on the same day of the diagnosis were evaluated. Echocardiographic findings of PE, such as right ventricular a/hypokinesis, interventricular septal shift and paradoxical movement and systolic pulmonary arterial pressure (sPAP) in addition to left ventricular ejection fraction were noted. Either interatrial septal defect (patent foramen ovale) or interventricular septal defect was not present in PE groups. The Statistical Package for the Social Sciences 20.0 (SPSS Inc, Chicago, IL, USA) was used for statistical analysis. The Kolmogorov�CSmirnov test was used to evaluate whether the [https://en.wikipedia.org/wiki/Itraconazole Itraconazole] variables were distributed normal or not. Continuous variables were expressed as mean (��) standard deviation or median (min-max) according to distribution state. Nominal variables were expressed as percentage. Student's t-test and/or Mann�CWhitney U-test were used to compare parametric or nonparametric variables between the PE and the control groups and between the massive and the submassive PE patients. The relationships between CTPAOIR [http://www.selleckchem.com/products/Vandetanib.html selleck chemicals] and the laboratory values [red cell distribution width (RDW), platelet, MPV, PDW, D-Dimer, hs-cTnT and arterial oxygen pressure (PaO2)], clinical probability scores (Wells and Geneva) were examined using the Spearman correlation coefficient analysis. Statistically significance was set at P value?[http://www.selleckchem.com/products/Verteporfin(Visudyne).html selleck compound] surgery (11.1%) and malignancies (11.1%). Twenty-four (38.1%) patients were free of any risk factors. The mean MPV and PDW values of patients with acute PE group were 10.92?��?1.37?fL and 13.31?��?2.22?fL, respectively. These values of healthy control subjects were 10.23?��?1.61?fL and 12.15?��?1.78?fL, respectively. There were statistically significant differences between groups in terms of MPV and PDW values (P?=?0.015 and P?=?0.003, respectively). The mean value of RDW was significantly different between two groups (P?