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Material and methods: Forty-one mini-implants were divided into two groups: 30 in the buccal and palatal mini-implants group (BPMI), inserted into buccal and palatal sides, and 11 in the midpalatal mini-implants group (MPMI), inserted into midpalatal suture. One day after insertion, a 200?gf was applied on the mini-implants [http://www.selleckchem.com/products/incb28060.html Selleckchem INCB28060] during a 5-month period. CBCT was performed twice: before force application (CBCT 1) and 5 months later (CBCT 2). For mini-implant displacement assessment, the distance of mini-implants' head (HMI) and tail (TMI) to coronal, sagittal and axial planes was measured at CBCT 1 and 2. Results: For the BPMI group, the displacement rate was statistically significant (P[http://www.selleckchem.com/products/gdc-0068.html GDC-0068 nmr] tomography. Clin. Oral Impl. Res. 22, 2011; 1151�C1156. doi: 10.1111/j.1600-0501.2010.02092.x ""To determine the difference in oral health�Crelated quality of life (OHRQoL) in patients who received mandibular 2-implant overdentures and conventional dentures in a pragmatic international study. In this prospective study, data were gathered from 203 edentulous patients (mean age, 68.8; SD: 10.4?years) at eight centres in North America, South America and Europe. The patients were provided with new mandibular conventional dentures or implant overdentures supported by 2 implants and ball attachments and opposed by conventional dentures. At baseline and at 6?months post-treatment, patients rated their oral health�Crelated quality of life using the OHIP-20. A significantly higher proportion of the participants in the implant group in North America reported improvement in both the psychological and the handicap domains, compared to those who received conventional dentures (93% vs. 52%; P?[http://en.wikipedia.org/wiki/Isotretinoin Isotretinoin] implant overdentures reported improvement in physical pain, compared to 66% in the conventional group (P?