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The reviewed data that helped stratify the groups included past medical history of CKD, serum creatinine and recovery of serum creatinine within 3 months. Hence, the improvement of renal function was reviewed by the difference in the admission creatinine and the lowest creatinine achieved or independence from dialysis if previously dialysis-requiring. AKI was defined as an improvement in admission serum creatinine [http://www.selleckchem.com/products/epacadostat-incb024360.html IDO inhibitor] of >50%.This group was further subdivided using the RIFLE criteria into ��Risk��, ��Injury�� and ��Failure�� [11]. Using a serum creatinine of  creatinine >291 ?mol/L. Those patients who recovered renal function partially (improvement in serum creatinine [http://www.selleckchem.com/products/MG132.html http://www.selleckchem.com/products/MG132.html] adherence to the definition could not be observed as follow-up data for up to 3 months was not available for most patients, who were lost to follow-up. Statistical analysis Continuous variables were expressed as mean �� standard deviation or median and interquartile range and compared using the [http://en.wikipedia.org/wiki/ATPase ATPase] Student t-test or the Wilcoxon rank-sum test, as appropriate. Categorical variables were expressed as proportions and compared with the chi-square or Fisher exact test, as appropriate. All statistical tests were two sided, and P