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The same procedure is carried out on the right side. Both bands are knotted, positioning the padding on the bulbospongiosus muscle at the urethral bulbar level, and anchored [http://www.selleckchem.com/products/epz-6438.html EPZ-6438 cell line] at four points by the lateral meshes. A transverse, left hypogastric incision about 2.5 cm in length is then made for housing the adjustable titanium port. The latter is fixed to the hypogastric subcutaneous tissue with Prolene 3/0 suture. Next, the subcutaneous tissue is dissected to form a superficial tunnel lateral to the spermatic cord (in the same way as for artificial sphincter preparation) extending to the implant site. A silicone connection is inserted through the tunnel joining the implant to the titanium port. Eight milliliters of saline solution is injected through the padding to achieve a degree of distension of the fixed implant, thereby applying slight compression upon the urethra. Layered closure of both incisions using loose Vicryl 3/0 stitches is then carried out. The bladder catheter is left in place for 24 hours and is removed before the patient is discharged. Oral antibiotic treatment is maintained up to 7 days after surgery. Subsequent follow�Cup comprises of a patient visit [http://en.wikipedia.org/wiki/Montelukast Montelukast Sodium] and micturition cystourethrography (MCU) four weeks after surgery to determine the objective and subjective implant results. Subsequent follow�Cups depend on the primary pathology. An evolutive assessment is made of patient continence by administering as many fillings through the titanium port as needed to secure full urinary continence. Figure 1 The surgical technique. A. Components. B. Perineal incision. C. Bulbar Urethra Movilized. D. Tunneler application. E. ATOMS in place. Demographic and personal data (age, gender, associated diseases) were collected along with information on the etiology, severity, characteristics, duration of UI, complementary tests, surgery times, complications and results obtained. The SPSS version 17.0 statistical package for MS Windows was used for descriptive analysis of the data with calculations of means, medians and percentages. Statistical comparisons were in turn made with the Pearson chi�Csquared test and the Fisher exact test, as applicable. Statistical significance was considered for p [http://www.selleckchem.com/Akt.html Akt assay] transurethral resection of the prostate in the remaining subject (7.2%). One patient had received radiotherapy (7.2%). Two patients (14.4%) had received another device for UI in the form of a Pro Act type paraurethral balloon; in both cases it had been removed due to spontaneous rupture of some element of the device more than 10 years after implantation. The clinical and demographic characteristics are shown in Table 1. The mean surgery time was 86.6 minutes (range 65�C115). There were no intraoperative complications.