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In the present study the patients had a mean EQ-5D score of 0.70, which is comparable to a study on patients undergoing surgical treatment for lumbar disc herniation, where scores improved from 0.3 before surgery to 0.7 one year after the operation [16]. This is still significantly lower than scores reported in an age and gender matched normal Danish population where the age-matched mean EQ-5D in the corresponding age group is 0.92 [13]. Assessing the five subscales of EQ-5D reveals that the number of patients responding ��No problem�� to the question regarding pain and discomfort was significantly lower than patients responding ��No problem�� to the other four questions (Table 3) (p?[http://www.selleckchem.com/products/Romidepsin-FK228.html FK228 mouse] comparing results between control groups and patient populations. Both the ODI and the EQ-5D consists of relatively few questions compared to SF-36. Therefore it is not surprising that the lowest response rate in the present study was obtained with the SF-36 questionnaire. Consisting of eight domains, there is a considerable risk of mass significance comparing SF-36 scores between populations. However, the discriminatory power regarding comparison with a norm score is approximately 10 points in a study population of 60 individuals. The scores obtained in the fracture population are therefore significantly reduced compared to the normal population (Fig. 1) (p?[http://en.wikipedia.org/wiki/GNAT2 GNAT2] of patients prior to surgical treatment for a degenerative lumbar disease [17]. This supports the finding from the ODI that fracture patients have moderate disability, but not at a level comparable to patients undergoing [http://www.selleckchem.com/products/bgj398-nvp-bgj398.html selleck products] surgical treatment of a degenerative condition. It could be argued that one weakness of this study is that no radiographic parameters were included. Numerous studies, however, have documented that loss of correction is not uniformly related to clinical outcome [18]?and?[19]. Also, the fracture distribution in the present study corresponds to previously reported studies [20]. Based on the findings in the present study patients who are undergoing posterior fixation for a thoracolumbar fracture can be informed that they are likely to experience reduced HRQL 2 to 6 years after the procedure but not to a degree corresponding to patients undergoing surgery for degenerative conditions of the spine. There are no conflict of interest for any author. This study was supported by a grant from The Danish Strategic Research Council (No. 2142-08-0017). ""According to a study by the F��d��ration Internationale de Football Association (FIFA), there are approximately 265 million active soccer players globally, a number that is only growing, making it the world's most popular sport [1].