Lyrebrain41: Створена сторінка: Acknowledgments The authors would prefer to thank Ms. Katie Lee for her assistance. SC would be the Canada Study Chair inside the Genetics of Obesity and Diabet...

2017-05-27T06:26:43Z

Створена сторінка: Acknowledgments The authors would prefer to thank Ms. Katie Lee for her assistance. SC would be the Canada Study Chair inside the Genetics of Obesity and Diabet...

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Acknowledgments The authors would prefer to thank Ms. Katie Lee for her assistance. SC would be the Canada Study Chair inside the Genetics of Obesity and Diabetes and also a Michael Smith Foundation for Health Analysis Scholar. Author Contributions Conceived and designed the experiments: SMC. Performed the experiments: MMH XH SK. Analyzed the information: MMH SMC. Contributed reagents/materials/analysis tools: JDJ. Wrote the paper: MMH SMC. Revised the manuscript: JDJ. References 1. Weir GC, Bonner-Weir S 5 stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 53 Suppl 3: S1621. two. Lyssenko V, Laakso M Genetic screening for the risk of form 2 diabetes: worthless or worthwhile Diabetes Care 36 Suppl 2: S120126. three. Florez JC Newly identified loci highlight beta cell dysfunction as a key reason for type 2 diabetes: where are the insulin resistance genes Diabetologia 51: 11001110. four. Morris AP, Voight BF, Teslovich TM, Ferreira T, Segre AV, et al. Largescale association evaluation delivers insights in to the genetic architecture and pathophysiology of form 2 diabetes. Nat Genet 44: 981990. five. Stahl EA, Wegmann D, Trynka G, Gutierrez-Achury J, Do R, et al. Bayesian inference analyses on the polygenic architecture of rheumatoid arthritis. Nat Genet 44: 483489. 6. Clee SM, Attie AD The genetic landscape of sort 2 diabetes in mice. Endocr Rev 28: 4883. 7. Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, et al. Positional cloning of a variety two diabetes quantitative trait locus; tomosyn-2, a adverse regulator of insulin secretion. PLoS Genet 7: e1002323. eight. Clee SM, Yandell BS, Schueler KM, Rabaglia ME, Richards OC, et al. Positional cloning of Sorcs1, a kind two diabetes quantitative trait locus. Nat Genet 38: 688693. 9. Goodarzi MO, Lehman DM, Taylor KD, Guo X, Cui J, et al. SORCS1: A Novel Human Kind 2 Diabetes Susceptibility Gene Recommended by the Mouse. Diabetes 56: 19221929. ten. Dokmanovic-Chouinard M, Chung WK, Chevre JC, Watson E, Yonan J, et al. Positional cloning of ��Lisch-Like'', a candidate modifier of susceptibility to type two diabetes in mice. PLoS Genet four: e1000137. 11. Scherneck S, Nestler M, Vogel H, Bluher M, Block MD, et al. Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL. PLoS Genet 5: e1000541. 12. Keane TM, Goodstadt L, Danecek P, White MA, Wong K, et al. Mouse genomic variation and its impact on phenotypes and gene [http://www.bucksportnext.net/vanilla/discussion/773734/gpcr-biology Gpcr Biology] regulation. Nature 477: 289294. 13. Roberts A, Pardo-Manuel de Villena F, Wang W, McMillan L, Threadgill DW The polymorphism architecture of mouse genetic sources elucidated making use of genome-wide resequencing data: implications for QTL discovery and systems genetics. Mamm Genome 18: 473481. 14. Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, et al. Genetic evaluation of complex traits within the emerging Collaborative Cross. Genome Res 21: 12131222. 15. Sanger Institute Mouse Genomes Project. http://www.sanger.ac.uk/ resources/mouse/genomes/. Accessed 2010 February 24. 16. Collaborative Cross Consortium The genome architecture of your Collaborative Cross mouse genetic reference population. Genetics 190: 389 401. 17. Lee KT, Karunakaran S, Ho MM, Clee SM PWD/PhJ and WSB/EiJ Mice Are Resistant to Diet-Induced Obesity But Have Abnormal Insulin Secretion. Endocrino

Phosphorylation Of Gpcr - Історія редагувань

Lyrebrain41: Створена сторінка: Acknowledgments The authors would prefer to thank Ms. Katie Lee for her assistance. SC would be the Canada Study Chair inside the Genetics of Obesity and Diabet...