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Thus, GENK can both stimulate CMV and SV40-promoter-dependent transcription and inhibit miR-122 activity
Thus, IL-6 seems to be partially involved in chemoresistance and only for a panel of agents, as suggested by the difference of cell behaviour in response to cisplatin and doxorubicin in our work
Thus, NFATs-HDACs complexes may play a role in the fine tuning of the process of catecholamine secretion via determination of the optimal expression profile
Thus, SNAP induces morphological changes related to those of cortical reaction, which are also observed for egg activation induced by calcium ionophore A23187
Thus, alternative splicing generates PMCA variants of different structure and biochemical properties, such as affinity for calcium ions
Thus, differentiation deficiencies in IEC-specific HDAC1/2 knockout mice may lead to altered responses to the microbial environment
Thus, dissecting out integrin-specific signals and crosstalk with environmental cues potentially holds the key to understanding
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Thus, in the epidermis, Wnt5a is most strongly expressed in the basal layer, while SFRP2 is highly expressed in suprabasal cells
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Thus, it was concluded that the enzymes consist as a four-layered abba structure, with a central, mostly anti-parallel b-sandwich that is surrounded by a-helices on both faces
Thus, our findings suggest that the VAMP721- and VAMP722-labeled vesicles and endosomal compartments sorted from TGN/early endosomal membrane domains are required for cell plate construction
Thus, semithin sections of 8 random samples of the left ventricular muscle including the septum were cut and examined by light microscopy with oil immersion and phase contrast at a magnification
Thus, the Legionella Dot/Icm system is assembled before bacteria engage host cells and initiates effector translocation once cell contact is sensed
Thus, the extent of selective interaction effects can be estimated by a systematic pattern of excess covariation specifically
Thus, the impairment was surprisingly not associated with the alteration in the predicted structure as suggested, but with a nucleotide change in the sequence
Thus, the lack of a trans-dominant negative effect upon overexpression of inactive Taspase1 mutants may be explained by inefficient heterocomplex formation in vivo
Thus, the mechanism underlying the observed association remains unclear and awaits further molecular investigations
Thus, the results indicate that GENK treatment induces an early inflammatory response
Thus, this finding further supports our hypothesis that silymarin inhibits melanoma cell migration by targeting b-catenin
Thus, this small loop region is a candidate to elicit CF release, although alone does not account for the extent of b-structure found in form B
Thus, treatment of IAV with extract RA appears to directly interfere with the cell surface receptor-binding function of IAV HA
Thus, we analysed proliferation rates of degenerative cervical NP cells and their endogenous expression levels of therapeutic target proteins in a three-dimensional collagen I scaffold
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Thus the lowered existence of Necdin in NIHLT cells sensitized them to p53 cell cycle arrest
Thus to boost the rank get in ways pharmacophoric modelling was used in this function as earlier proposed by other people
Thus to enhance the rank get in approaches pharmacophoric modelling was utilized in this perform as beforehand proposed by others
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