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Thus, GENK can both stimulate CMV and SV40-promoter-dependent transcription and inhibit miR-122 activity
Thus, IL-6 seems to be partially involved in chemoresistance and only for a panel of agents, as suggested by the difference of cell behaviour in response to cisplatin and doxorubicin in our work
Thus, NFATs-HDACs complexes may play a role in the fine tuning of the process of catecholamine secretion via determination of the optimal expression profile
Thus, SNAP induces morphological changes related to those of cortical reaction, which are also observed for egg activation induced by calcium ionophore A23187
Thus, alternative splicing generates PMCA variants of different structure and biochemical properties, such as affinity for calcium ions
Thus, differentiation deficiencies in IEC-specific HDAC1/2 knockout mice may lead to altered responses to the microbial environment
Thus, dissecting out integrin-specific signals and crosstalk with environmental cues potentially holds the key to understanding
Thus, each trial type was associated with ``migraine'', ``nausea'', or ``no outcome''. Each participant completed two sets of FN discrimination and related control trials
Thus, in the epidermis, Wnt5a is most strongly expressed in the basal layer, while SFRP2 is highly expressed in suprabasal cells
Thus, it is unlikely that the reduced MMP-8 staining in ATII cells in IPF lungs is due to reduced viability of these cells
Thus, it was concluded that the enzymes consist as a four-layered abba structure, with a central, mostly anti-parallel b-sandwich that is surrounded by a-helices on both faces
Thus, our findings suggest that the VAMP721- and VAMP722-labeled vesicles and endosomal compartments sorted from TGN/early endosomal membrane domains are required for cell plate construction
Thus, semithin sections of 8 random samples of the left ventricular muscle including the septum were cut and examined by light microscopy with oil immersion and phase contrast at a magnification
Thus, the Legionella Dot/Icm system is assembled before bacteria engage host cells and initiates effector translocation once cell contact is sensed
Thus, the extent of selective interaction effects can be estimated by a systematic pattern of excess covariation specifically
Thus, the impairment was surprisingly not associated with the alteration in the predicted structure as suggested, but with a nucleotide change in the sequence
Thus, the lack of a trans-dominant negative effect upon overexpression of inactive Taspase1 mutants may be explained by inefficient heterocomplex formation in vivo
Thus, the mechanism underlying the observed association remains unclear and awaits further molecular investigations
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Thus, this finding further supports our hypothesis that silymarin inhibits melanoma cell migration by targeting b-catenin
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Tid1 is a p53-interacting protein that helps this localization from the nucleus to mitochondria
Tid1 is a p53-interacting protein that will help this localization from the nucleus to mitochondria
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