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- Because FGF signaling enhances multiple biological processes that promote tumor progression, it is an attractive therapeutic target
- Because of the close homology between mouse and rat the sequence of shRNA was the same as the one which induced growth stimulation
- Because of the modular nature of these antidotes, it should be straightforward to develop similar agents targeting all seven BoNT serotypes and subtypes by substituting the VHH with other VHHs having the appropriate specificity
- Because the biochemical circumstance of flatworm parasites is really comparable with regards to the thiol redox-dependent pathways
- Because the group of genes proven in Table S2 most carefully correlates with PyLT expression at the transcriptional level
- Because we had observed a HIF1-dependent increase in OxPhos in complete media, we wanted to assess how the levels of glycolytic acid production and oxygen consumption were influenced by Pdk1 expression in this model system
- Because we observed suppression of ovarian tumors by oral administration of PEITC, we hypothesized that development inhibitory effects of PEITC in ovarian tumors in vivo were by means of inhibition of EGFR-AKT
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