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(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).
- 08:22, 24 січня 2018 (різн. • історія) . . (+5010) . . Н Final results reported listed here assist this dual performance for Necdin p53-dependent tumor suppressive cell fates (Створена сторінка: Furthermore, translation from the RPA39 mutant promoter was initiated from the indigenous downstream AUG, but in this scenario there was a considerable leakage...) (поточна)
- 08:12, 24 січня 2018 (різн. • історія) . . (+4904) . . Н Necdin was 1st recognized as a neuronal differentiation marker linked with growth arrest but has because been discovered (Necdin was 1st recognized as a neuronal differentiation marker linked with growth arrest but has because been discovered) (поточна)
- 11:36, 23 січня 2018 (різн. • історія) . . (+5381) . . Н Necdin is a p53 target gene and physically interacts with the p53 protein product suggesting a useful romantic relationship (Створена сторінка: In particular, the tip of a310 loop reaches across the rigid b barrel creating several contacts with PBC. The aspect chain of Asn116 kinds a hydrogen bond with...) (поточна)
- 12:18, 22 січня 2018 (різн. • історія) . . (+5301) . . Н The easy substitution of the para-hydroxy group on curcumin with a methoxy substitution enhanced inhibitor operate (Створена сторінка: In particular, the suggestion of a310 loop reaches throughout the rigid b barrel generating numerous contacts with PBC. The facet chain of Asn116 kinds a hydrog...) (поточна)
- 11:48, 19 січня 2018 (різн. • історія) . . (+5404) . . Н The basic substitution of the para-hydroxy team on curcumin with a methoxy substitution enhanced inhibitor operate (Створена сторінка: In distinct, the tip of a310 loop reaches across the rigid b barrel making multiple contacts with PBC. The aspect chain of Asn116 varieties a hydrogen bond with...) (поточна)
- 11:40, 17 січня 2018 (різн. • історія) . . (+5365) . . Н The progression of Advertisement and improve cognitive operate based on its intramembrane cleavage (Створена сторінка: In certain, the idea of a310 loop reaches throughout the rigid b barrel producing numerous contacts with PBC. The aspect chain of Asn116 types a hydrogen bond w...) (поточна)
- 08:57, 12 січня 2018 (різн. • історія) . . (+5417) . . Н The most basic responsibilities usually this situation interferes strongly with most day-to-day routines issues (Створена сторінка: In certain, the suggestion of a310 loop reaches across the rigid b barrel making several contacts with PBC. The facet chain of Asn116 forms a hydrogen bond with...) (поточна)
- 09:05, 10 січня 2018 (різн. • історія) . . (+6805) . . Н At current there is no cure for PD but a variety of palliatives decreasing the severity of disease signs and symptoms exists (Створена сторінка: One particular of us predicted beforehand that the cytoplasmic finish of CHL1 protein may possibly interact with the cytoskeleton and might induce/[http://www.a...) (поточна)
- 08:54, 10 січня 2018 (різн. • історія) . . (+4802) . . Н The most thoroughly analyzed pathology within a team of syndromes named motor program disorders whose etiology can be traced (The most thoroughly analyzed pathology within a team of syndromes named motor program disorders whose etiology can be traced) (поточна)
- 09:13, 9 січня 2018 (різн. • історія) . . (+6607) . . Н We and other people also observed soft diarrhea-like stool of the animals soon after systemic injection following the injection (Створена сторінка: The protein transduction area transports the fused proteins into cells and makes it possible for them to distribute all through the body by passive diffusion. I...) (поточна)
- 10:25, 8 січня 2018 (різн. • історія) . . (+6798) . . Н Moreover treatment method qualified prospects to behavioral inactivity and leads to rats to lie quietly on the ground of the cage and elicits diarrhea (Створена сторінка: A single of us predicted formerly that the cytoplasmic conclude of CHL1 protein may interact with the cytoskeleton and may well induce/control filopodia formati...) (поточна)
- 10:15, 8 січня 2018 (різн. • історія) . . (+4800) . . Н In distinction NREM slumber occurrence is only marginally influenced by lithium administration decreases the relative delta energy (Створена сторінка: A wonderful number of in vitro experiments showed that ROS damages DNA, which appears to represent the main concentrate on associated in mutagenesis, carcinogen...) (поточна)
- 10:18, 5 січня 2018 (різн. • історія) . . (+6826) . . Н In addition treatment method prospects to behavioral inactivity and leads to rats to lie quietly on the flooring of the cage and elicits diarrhea (Створена сторінка: 1 of us predicted beforehand that the cytoplasmic conclude of CHL1 protein may well interact with the cytoskeleton and may induce/control filopodia formation dr...) (поточна)
- 10:06, 5 січня 2018 (різн. • історія) . . (+4814) . . Н In contrast NREM sleep occurrence is only a bit impacted by lithium administration reduces the relative delta electrical power (Створена сторінка: A wonderful variety of in vitro experiments confirmed that ROS damages DNA, which appears to represent the significant concentrate on associated in mutagenesis,...) (поточна)
- 10:59, 4 січня 2018 (різн. • історія) . . (+6825) . . Н Ventromedial hypothalamic lesion is connected with increased snooze time in rats on slumber in mice (Створена сторінка: 1 of us predicted earlier that the cytoplasmic conclude of CHL1 protein may possibly interact with the cytoskeleton and might induce/regulate filopodia formatio...) (поточна)
- 10:48, 4 січня 2018 (різн. • історія) . . (+4840) . . Н Improved feeding induced by prior foodstuff deprivation elicits postprandial sleep thermogenesis by suppressing (Створена сторінка: A excellent number of in vitro experiments showed that ROS damages DNA, which seems to represent the significant focus on concerned in mutagenesis, carcinogenes...) (поточна)
- 12:26, 2 січня 2018 (різн. • історія) . . (+6646) . . Н Leads to boosts in slumber and adiposity alerts are very likely to mediate the effects of good vitality states on snooze (Створена сторінка: The protein transduction domain [http://www.abmole.com/products/doxorubicin.html Adriamycin] transports the fused proteins into cells and permits them to unfold...) (поточна)
- 12:15, 2 січня 2018 (різн. • історія) . . (+4854) . . Н There is a recognized connection between feeding metabolic rate and snooze the side results induced by this drug (Створена сторінка: We have freshly uncovered an further cluster of highly conserved proline-abundant motifs on the C-terminus of bestrophin-one and demonstrate that this cluster i...) (поточна)
- 09:16, 29 грудня 2017 (різн. • історія) . . (+4929) . . Н Taken care of with enzastaurin to enzastaurin and was linked with similar alterations in the expression of p27Kip1 (Створена сторінка: A excellent amount of in vitro experiments showed that ROS damages DNA, which seems to depict the key concentrate on concerned in mutagenesis, carcinogenesis an...) (поточна)
- 10:03, 27 грудня 2017 (різн. • історія) . . (+6717) . . Н With enhanced efficiency and a lot more favourable pharmacokinetic homes may possibly also be lively towards (Створена сторінка: The protein transduction area transports the fused proteins into cells and enables them to unfold during the entire body by passive diffusion. In the current st...) (поточна)
- 09:52, 27 грудня 2017 (різн. • історія) . . (+4859) . . Н These knowledge present that our composition is also a good doing work product of the adenine-binding pocket (Створена сторінка: A great amount of in vitro experiments confirmed that ROS damages DNA, which appears to depict the major concentrate on associated in mutagenesis, carcinogenesi...) (поточна)
- 11:32, 25 грудня 2017 (різн. • історія) . . (+6506) . . Н These data present that our framework is also a great operating product of the adenine-binding pocket (Створена сторінка: Burrowing changes started out at eight dpi and recovered to management levels at 13 dpi. Open-field assessments introduced important variations between IEPy and...) (поточна)
- 11:08, 22 грудня 2017 (різн. • історія) . . (+6258) . . Н Assist to seal the substrate and cofactor binding websites for the chemical transfer of a pyrophosphate from ATP to HMDP (Створена сторінка: In addition, by learning the binding to Diva of Harakiri constructs of various length we determine the crucial region for binding in Harakiri and observe that a...) (поточна)
- 07:48, 21 грудня 2017 (різн. • історія) . . (+6681) . . Н The feasibility of creating new inhibitors based mostly on bisubstrate-linking HPPK shares sequence homology (Створена сторінка: The protein transduction domain transports the fused proteins into cells and permits them to unfold through the entire body by passive diffusion. In the existin...) (поточна)
- 07:26, 20 грудня 2017 (різн. • історія) . . (+6838) . . Н The two are based mostly on the pterin substrate a single featuring gem-dimethyl substitution at the placement on the pyrimidine ring (Створена сторінка: One particular of us predicted earlier that the cytoplasmic finish of CHL1 protein may possibly interact with the cytoskeleton and may well induce/control filop...) (поточна)
- 07:13, 20 грудня 2017 (різн. • історія) . . (+6289) . . Н Help to seal the substrate and cofactor binding internet sites for the chemical transfer of a pyrophosphate from ATP to HMDP (Створена сторінка: In addition, by researching the binding to Diva of Harakiri constructs of diverse duration we identify the essential location for binding in Harakiri and notice...) (поточна)
- 10:57, 19 грудня 2017 (різн. • історія) . . (+6226) . . Н In purchase to evaluate the protein-ligand interactions the ligands of the diverse X-ray structures (Створена сторінка: In addition, by studying the binding to Diva of Harakiri constructs of different duration we determine the critical location for binding in Harakiri and observe...) (поточна)
- 08:06, 15 грудня 2017 (різн. • історія) . . (+6877) . . Н The relevance of this amino acid residue was presently postulated proposed to concentrate on it in the inhibitor style method (Створена сторінка: One particular of us predicted beforehand that the cytoplasmic stop of CHL1 protein might interact with the cytoskeleton and may possibly induce/control filopod...) (поточна)
- 07:53, 15 грудня 2017 (різн. • історія) . . (+6532) . . Н The reason for this is the residue Arg258 which protrudes into the active internet site in circumstance of 1equ (Створена сторінка: Burrowing alterations commenced at eight dpi and recovered to control stages at thirteen dpi. Open up-field checks introduced considerable variations amongst IE...) (поточна)
- 09:48, 11 грудня 2017 (різн. • історія) . . (+6120) . . Н Regression in all dealt with animals with out evidence of ailment at the conclude of the experiment with antimicrotubule agents (Створена сторінка: A mounting body of evidence implies that malignant cells display global miRNA silencing. Modern experimental evidence indicates DICER gene deletion in mouse mod...) (поточна)
- 09:45, 4 грудня 2017 (різн. • історія) . . (+4832) . . Н Furthermore we report the results of the Nglycans and the NH2-terminus on the charge of inhibition of PSA (Створена сторінка: Oral administration of 100 mg/kg provided ideal efficacy in mice in opposition to ectromelia virus. Exposure following the oral a hundred mg/kg doses was near t...) (поточна)
- 12:37, 16 листопада 2017 (різн. • історія) . . (+4817) . . Н Contributing to the depletion of oleic acid and secondary enrichment in arachidonic acid (Contributing to the depletion of oleic acid and secondary enrichment in arachidonic acid) (поточна)
- 11:04, 3 листопада 2017 (різн. • історія) . . (+6308) . . Н Contribute to binding affinity through water-mediated hydrogen bonds carcinoma cells to comply with SCITs (Створена сторінка: The chicken genome only have the mammalian orthologue of ERK2 suggesting that this gene later on duplicated itself and evolved into ERK1 in a mammalian progenit...) (поточна)
- 11:08, 2 листопада 2017 (різн. • історія) . . (+7159) . . Н Even though the system for these observations was not proven in this review genomes revealed mutations (Створена сторінка: Because B-cells with a mutation in TLR4 had been unable to proliferate in the presence of rpHsp90, it could be considered that TLR4 is at least 1 of the recepto...) (поточна)
- 10:17, 27 жовтня 2017 (різн. • історія) . . (+4616) . . Н However kinases knockdown has a limitation in circumstance of really steady proteins as VRKs because in RNA interference experiments (However kinases knockdown has a limitation in circumstance of really steady proteins as VRKs because in RNA interference experiments) (поточна)
- 12:14, 20 жовтня 2017 (різн. • історія) . . (+4776) . . Н Through the membrane far more successfully and is consequently accountable for the biological exercise that is minimal provided (Створена сторінка: For that reason, we sought to examine the effectiveness of Ha7-mediated fusion with that of a standard PEGmediated fusion protocol. In this case, 293T cells had...) (поточна)
- 09:59, 19 жовтня 2017 (різн. • історія) . . (+4848) . . Н Dependent on the clients age intercourse concomitant illnesses medication and diet program that are inhibitors (Створена сторінка: Consequently, we sought to examine the performance of Ha7-mediated fusion with that of a normal PEGmediated fusion protocol. In this circumstance, 293T cells ha...) (поточна)
- 14:34, 16 жовтня 2017 (різн. • історія) . . (+4744) . . Н The regular transpeptidation response this last but not least results in bacterial death to current antimicrobials (Створена сторінка: Therefore, we sought to compare the performance of Ha7-mediated fusion with that of a regular PEGmediated fusion protocol. In this case, 293T cells ended up eit...) (поточна)
- 11:37, 13 жовтня 2017 (різн. • історія) . . (+4988) . . Н As they are constantly current in described all-natural variants are evidently important (Створена сторінка: In buy to recognize immunostaining for microscopic evaluation, gastric sections ended up quickly thawned and saturated for one hour at 4uC in PBS0+,two% Bovine...) (поточна)
- 08:43, 12 жовтня 2017 (різн. • історія) . . (+4922) . . Н Have been published though no clinically useful inhibitor is identified (Створена сторінка: In purchase to comprehend immunostaining for microscopic assessment, gastric sections ended up speedily [http://cryptogauge.com/members/anger06waste/activity/17...) (поточна)
- 07:07, 10 жовтня 2017 (різн. • історія) . . (+4929) . . Н This similarity in SAR supports the speculation that the hydroxyphenyl moieties of equally compound (Створена сторінка: Concerning studies on rat pups, animal experiments ended up realized according to the principles of the Nantes animal experimental unit and the Rules of laborat...) (поточна)
- 07:35, 9 жовтня 2017 (різн. • історія) . . (+5033) . . Н Examined ended up changed by compounds in accordance to their pharmacophoric binding modes (Створена сторінка: As observed in Determine 2B, the quantity of double-constructive cells increased with time, suggesting stochastic activation of the redifferentiation process, r...) (поточна)
- 07:23, 9 жовтня 2017 (різн. • історія) . . (+4873) . . Н This similarity in SAR supports the hypothesis that the hydroxyphenyl moieties of both compound (Створена сторінка: Regarding scientific studies on rat pups, animal experiments had been realized in accordance to the rules of the Nantes animal experimental unit and the Rules o...) (поточна)
- 09:37, 29 вересня 2017 (різн. • історія) . . (+5114) . . Н This is proved by regimen clinic use of different endocrine therapies for instance with GnRH analogues (Створена сторінка: As noticed in Figure 2B, the amount of double-good cells enhanced with time, suggesting stochastic activation of the redifferentiation approach, instead than a...) (поточна)
- 05:38, 28 вересня 2017 (різн. • історія) . . (+4794) . . Н Among feminine sex hormones 17b-estradiol is the most strong estrogen carrying out its action either (Створена сторінка: On the opposite, the 59UTR-G243A could not compensate the NS2-F14L, NS2-Q212K and NS3-A621T variants. Moreover, distinct kinds of codon usage had been released...) (поточна)
- 16:32, 27 вересня 2017 (різн. • історія) . . (+4799) . . Н In each the human male and female reproductive techniques for DC-Indication in seminal plasma (Створена сторінка: On the contrary, the 59UTR-G243A could not compensate the NS2-F14L, NS2-Q212K and NS3-A621T variants. In addition, distinct varieties of codon utilization were...) (поточна)
- 05:35, 25 вересня 2017 (різн. • історія) . . (+4433) . . Н Due to the versatility of PCI the mechanisms of regulation of its various features are intriguing (Створена сторінка: Electrostatic potentials at the area of the PTP99A D2 area highlight the unfavorable expenses, which are fairly unusual in the phosphotyrosine binding pocket of...) (поточна)
- 09:11, 21 вересня 2017 (різн. • історія) . . (+4593) . . Н We do not know the specific system of this compounds motion modifies PLP or regulates its purpose (Створена сторінка: Apparently, in the circumstance of PTP99A, the residues of the WPD loop shaped a different cluster from the lively site when the D1 area was current by yourself...) (поточна)
- 08:29, 20 вересня 2017 (різн. • історія) . . (+4740) . . Н The transfer of mycolic acids from trehalose monomycolate to trehalose dimycolate is catalyzed (Створена сторінка: The total expression pattern of the transgene in Thy1-maSN was also really equivalent to those noted for the two traces expressing haSN under the manage Thy1 re...) (поточна)
- 05:57, 19 вересня 2017 (різн. • історія) . . (+4596) . . Н Focused by the very first-line anti-tuberculars isoniazid and ethambutol (Створена сторінка: Interestingly, in the scenario of PTP99A, the residues of the WPD loop formed a separate cluster from the energetic site when the D1 domain was present by yours...) (поточна)
(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).