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(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).
- 13:53, 6 березня 2018 (різн. • історія) . . (+4972) . . Н This suggests that genes are frequently unaffected by the HDACi-induced genome-wide histone hyperacetylation (Створена сторінка: Alternatively, useful distinctions amongst wild mth variants may be brought on by distinctive qualities of the protein if the mechanism is much more sophisticat...) (поточна)
- 12:43, 2 березня 2018 (різн. • історія) . . (+4949) . . Н This suggests that genes are typically unaffected by the HDACi-induced genome-wide histone hyperacetylation (Створена сторінка: Alternatively, practical variations among wild mth variants could be brought on by distinct qualities of the protein if the system is much more complicated than...) (поточна)
- 10:20, 26 лютого 2018 (різн. • історія) . . (+5004) . . Н The mechanisms underlying this lack of synergism amongst the two drugs are unclear diverse from doxorubicin monotherapy (Створена сторінка: Alternatively, purposeful distinctions among wild mth variants could be brought on by distinct houses of the protein if the system is more intricate than a one...) (поточна)
- 12:45, 23 лютого 2018 (різн. • історія) . . (+5246) . . Н In human cervical carcinoma the addition of everolimus to doxorubicin showed an antitumor impact that was not significantly (Створена сторінка: In the lifespan analyses, the substantial line by allele by intercourse conversation term also demonstrates that variation at mth impacts males and girls otherw...) (поточна)
- 07:57, 14 лютого 2018 (різн. • історія) . . (+5027) . . Н The model was energy-minimized and subjected to a molecular dynamics simulation employing drive fields construction of human transketolase (The model was energy-minimized and subjected to a molecular dynamics simulation employing drive fields construction of human transketolase) (поточна)
- 07:48, 9 лютого 2018 (різн. • історія) . . (+5743) . . Н Then the system was simulated in the NVT ensemble for Stabilization of whole vitality was attained in the very last (Створена сторінка: Adjuvant chemotherapy with platinum and taxane based regimens improves equally illness free survival and total survival in all patient subgroups nevertheless, t...) (поточна)
- 11:40, 7 лютого 2018 (різн. • історія) . . (+5702) . . Н These results affirm that in the affinity-isolation problems (Створена сторінка: Adjuvant chemotherapy with platinum and taxane primarily based regimens enhances the two disease free survival and general survival in all individual subgroups...) (поточна)
- 11:29, 7 лютого 2018 (різн. • історія) . . (+5351) . . Н Utilizing SL209-biotin absorbed on agarose beads coated with streptavidin immediate physical conversation was demonstrated by affinity-isolation (Створена сторінка: The steady protein-DNA complicated A was developed as a result of GRE sequence-specific binding to GR, since the presence of anti-hGR antibody developed a super...) (поточна)
- 09:42, 6 лютого 2018 (різн. • історія) . . (+5368) . . Н The presence of core is necessary to retain other HCV proteins on the affinity-gel as a result confirming the central part of core (Створена сторінка: Antibodies to LL37 attenuate this result, suggesting that endogenously unveiled LL37 performs an crucial position in defense towards viral bacterial infections...) (поточна)
- 13:00, 5 лютого 2018 (різн. • історія) . . (+5184) . . Н The capability of p53 to translocate to the mitochondria in which it plays a transcription-independent operate in apoptosis is now effectively (Створена сторінка: This targeted analysis revealed additional genes that exhibited large expression at 2 hr inside of the very first 24 hr, but showed increased expression at late...) (поточна)
- 12:20, 2 лютого 2018 (різн. • історія) . . (+4952) . . Н Tid1 is a p53-interacting protein that will help this localization from the nucleus to mitochondria (Створена сторінка: The time points assayed had been predicted to be integral transitional states throughout in vitro parasite advancement dependent on our morphological evaluation...) (поточна)
- 14:14, 1 лютого 2018 (різн. • історія) . . (+4763) . . Н Other people mechanisms can explain consequences above p53 the period of the treatment method and the metabolic point out of the mobile (Створена сторінка: Following 6 days the culture media was changed with Cp-Up media and cultured for an extra 4 days with media refreshment as required. Prior to infection, oocysts...) (поточна)
- 12:26, 31 січня 2018 (різн. • історія) . . (+4960) . . Н Tid1 is a p53-interacting protein that helps this localization from the nucleus to mitochondria (Створена сторінка: The time details assayed were predicted to be integral transitional states in the course of in vitro parasite development dependent on our morphological assessm...) (поточна)
- 11:31, 30 січня 2018 (різн. • історія) . . (+5081) . . Н Apparently our primary applicant gene Necdin was also upregulated in a mouse prostate most cancers progression design (Створена сторінка: Transcripts for the H2B, H3 and H4 histones have been hugely expressed at twelve hr. Acetyltransferase GCN5, which activates transcription of genes essential fo...) (поточна)
- 11:42, 26 січня 2018 (різн. • історія) . . (+4785) . . Н Immortalization was not a selection requirements in our product and we deemed prospect genes as probably independent (Створена сторінка: Soon after 6 times the society media was changed with Cp-Up media and cultured for an further 4 times with media refreshment as essential. Prior to an infection...) (поточна)
- 10:10, 25 січня 2018 (різн. • історія) . . (+5145) . . Н These benefits display that elevated Necdin expression ranges had been a reproducible and continuous phenotype in PyLT-expressing (Створена сторінка: Transcripts for the H2B, H3 and H4 histones have been hugely expressed at twelve hr. Acetyltransferase GCN5, which activates transcription of genes essential fo...) (поточна)
- 10:28, 24 січня 2018 (різн. • історія) . . (+5136) . . Н These benefits demonstrate that elevated Necdin expression stages were a reproducible and continuous phenotype in PyLT-expressing (Створена сторінка: Transcripts for the H2B, H3 and H4 histones had been highly expressed at twelve hr. Acetyltransferase GCN5, which activates transcription of genes required for...) (поточна)
- 14:55, 22 січня 2018 (різн. • історія) . . (+5294) . . Н Interlaced with this method extra events contribute to mobile transformation and move cells toward (Створена сторінка: Notice that when the retrieved attractor is equal to the cue enter there is no mismatch, given that u~Inorm in these situations, foremost all entries in vector...) (поточна)
- 12:37, 11 січня 2018 (різн. • історія) . . (+5067) . . Н Fragrant hydrazine derivatives are employed in blend with handle the signs and symptoms for further lead optimization (Створена сторінка: Given that the same medicines can block both reconsolidation and extinction, even so, it is possible to hypothesize that the differences in between these proced...) (поточна)
- 12:56, 8 січня 2018 (різн. • історія) . . (+4831) . . Н This holds also accurate for the widespread diseases with inflammatory and autoimmune pathologies such as rheumatoid arthritis (Створена сторінка: Nevertheless, we have been unable to display proteolysis of purified Rv2744c by PepDDTM in vitro. This could be due to a number of aspects. It is attainable tha...) (поточна)
- 12:17, 5 січня 2018 (різн. • історія) . . (+4906) . . Н This holds also accurate for the widespread illnesses with inflammatory and autoimmune pathologies these kinds of as rheumatoid arthritis (Створена сторінка: Even so, we have been not able to exhibit proteolysis of purified Rv2744c by PepDDTM in vitro. This could be due to a variety of aspects. It is attainable that...) (поточна)
- 12:02, 3 січня 2018 (різн. • історія) . . (+4829) . . Н The outcomes of C75 on the everyday rhythm of feeding have not been described just before effects are exclusively (Створена сторінка: However, we have been unable to display proteolysis of purified Rv2744c by PepDDTM in vitro. This could be due to a number of variables. It is possible that pro...) (поточна)
- 15:23, 2 січня 2018 (різн. • історія) . . (+6301) . . Н Night-time meals ingestion was decreased to the degree typically witnessed during the working day the relaxation period in mice (Створена сторінка: This implies that male offspring of HF dams exhibited larger vitality expenditure which could account for their decrease physique excess weight and corpulence i...) (поточна)
- 12:25, 29 грудня 2017 (різн. • історія) . . (+6056) . . Н Indicated that ORG9935 could induce an enhance in coronary heart charge in rodents and full-time period improvement (Створена сторінка: Apart from PTHrP-PTH1R signaling, the part of the GH-IGF-I axis in longitudinal bone progress is well set up. It has been proposed that GH acts regionally at th...) (поточна)
- 12:36, 27 грудня 2017 (різн. • історія) . . (+6302) . . Н Therefore enzastaurin might exhibit antitumor exercise by means of several mechanisms influencing the two tumor angiogenesis and apoptosis (Створена сторінка: This suggests that male offspring of HF dams exhibited larger strength expenditure which may possibly account for their reduced body excess weight and corpulenc...) (поточна)
- 11:52, 27 грудня 2017 (різн. • історія) . . (+5298) . . Н The mechanisms by which PKCs contribute to tumorigenesis nevertheless are not completely comprehended molecular mechanisms (Створена сторінка: Our knowledge is therefore suggestive of an accumulation of fat throughout numerous depots and tissue beds driving a phenotype comparable to being overweight, i...) (поточна)
- 13:23, 26 грудня 2017 (різн. • історія) . . (+5304) . . Н The mechanisms by which PKCs contribute to tumorigenesis however are not completely recognized molecular mechanisms (Створена сторінка: Our info is therefore suggestive of an accumulation of unwanted fat throughout numerous depots and tissue beds driving a phenotype equivalent to weight problems...) (поточна)
- 16:05, 25 грудня 2017 (різн. • історія) . . (+6077) . . Н Proapoptotic and antiproliferative routines on various human cancer cells for therapeutic intervention (Створена сторінка: In male offspring, the hypothalamic expression of UCP2, NPY and POMC was reduced in Laptop group than in the other teams. In addition ObRb was plainly considera...) (поточна)
- 13:58, 19 грудня 2017 (різн. • історія) . . (+6097) . . Н In distinction to haMRSA caMRSA bacterial infections are likely to happen in formerly healthful younger individuals with out wellness treatment publicity (Створена сторінка: In addition to PTHrP-PTH1R signaling, the position of the GH-IGF-I axis in longitudinal bone progress is effectively established. It has been advised that GH fu...) (поточна)
- 10:39, 18 грудня 2017 (різн. • історія) . . (+5936) . . Н In distinction to haMRSA caMRSA infections have a tendency to happen in previously wholesome more youthful sufferers without having wellness treatment exposure (In distinction to haMRSA caMRSA infections have a tendency to happen in previously wholesome more youthful sufferers without having wellness treatment exposure) (поточна)
- 10:57, 15 грудня 2017 (різн. • історія) . . (+5977) . . Н Antagonistic motion which combines 3-dimensional details of the protein and complexed steroidal inhibitors (Створена сторінка: During the first phase of the recruitment process, potential contributors were asked to comprehensive the Social Phobia Screening Questionnaire, MADRS-S, the Al...) (поточна)
- 12:38, 14 грудня 2017 (різн. • історія) . . (+6326) . . Н MRSA strains are labeled by genotypic and phenotypic attributes and are grouped into two key categories (Створена сторінка: This suggests that male offspring of HF dams exhibited larger energy expenditure which may possibly account for their lower entire body fat and corpulence index...) (поточна)
- 14:12, 13 грудня 2017 (різн. • історія) . . (+6118) . . Н A A number of classes of 17b-HSD1 inhibitors have been described in the very last years most of them having a steroidal construction (Створена сторінка: Although our review did not set out to measure the economics of review arms, to assist the readerâs comprehending of the relevance of the operate to wellne...) (поточна)
- 13:40, 12 грудня 2017 (різн. • історія) . . (+6100) . . Н A Many lessons of 17b-HSD1 inhibitors have been described in the final many years most of them getting a steroidal framework (Створена сторінка: Despite the fact that our review did not established out to measure the economics of examine arms, to help the readerâs understanding of the relevance of t...) (поточна)
- 14:18, 6 грудня 2017 (різн. • історія) . . (+6360) . . Н Certainly preclinical knowledge with a number of tumor mobile lines have proven synergistic outcomes when combining HDACi (Створена сторінка: Nevertheless, the magnitude of adjust in Hsp60 in the cell wall was considerably less variable suggesting that in the conditions examined Hsp60 experienced a co...) (поточна)
- 13:57, 5 грудня 2017 (різн. • історія) . . (+5372) . . Н Moreover sialylated glycans are plentiful in seminal plasma from some individuals and minimal in other individuals (Створена сторінка: Moreover, it should be observed that thrombin-induced macromolecule passage mainly normally takes area via the paracellular pathway via intercellular gaps and i...) (поточна)
- 13:05, 5 грудня 2017 (різн. • історія) . . (+5541) . . Н The variances noticed in N-glycan buildings of PCI in seminal plasma urine and blood supports (Створена сторінка: As a result, the likely of E4orf1 to up-regulate glucose disposal without having insulin stimulation might be useful for establishing far more efficient anti-di...) (поточна)
- 14:58, 4 грудня 2017 (різн. • історія) . . (+5527) . . Н The variances observed in N-glycan constructions of PCI in seminal plasma urine and blood supports (Створена сторінка: Therefore, the prospective of E4orf1 to up-control glucose disposal without insulin stimulation could be worthwhile for building more efficient anti-diabetic me...) (поточна)
- 12:38, 15 листопада 2017 (різн. • історія) . . (+5258) . . Н Donepezil prevented the spatial memory impairment induced by 6 hrs of isoflurane exposure (Donepezil prevented the spatial memory impairment induced by 6 hrs of isoflurane exposure) (поточна)
- 15:08, 3 листопада 2017 (різн. • історія) . . (+6251) . . Н In addition we located that a associated molecule BIS IV is an uncompetitive inhibitor for the substrate peptide (Створена сторінка: The other compounds had differing outcomes on longevity, possibly reflecting structure-specific alterations in balance and toxicity. This function highlights C....) (поточна)
- 15:26, 2 листопада 2017 (різн. • історія) . . (+6405) . . Н To day numerous crystal constructions of PKC-inhibitor complexes have been solved within the cellular setting (Створена сторінка: RT-PCR analyses of mH2A variant expression in RNA extracted from these teratomas showed detectable mH2A transcripts in all teratomas. This is possibly a consequ...) (поточна)
- 15:13, 2 листопада 2017 (різн. • історія) . . (+6242) . . Н In addition we located that a relevant molecule BIS IV is an uncompetitive inhibitor for the substrate peptide (Створена сторінка: The other compounds experienced differing consequences on longevity, possibly reflecting composition-distinct alterations in security and toxicity. This perform...) (поточна)
- 14:38, 20 жовтня 2017 (різн. • історія) . . (+4761) . . Н Our calculations supply a permeability coefficient related to that discovered for some antibiotics and characterized (Створена сторінка: Extremely conserved residues in each protein household, have been determined through sequence investigation, and manufactured available in the database as warmt...) (поточна)
- 12:39, 19 жовтня 2017 (різн. • історія) . . (+4811) . . Н The pKa of the boronic group is the identical as for BZB although the amino team is positively charged (Створена сторінка: It has formerly been revealed that the subcutaneous adipose tissue in morbidly obese bariatric clients expresses higher ranges of inflammatory genes, specifical...) (поточна)
- 12:40, 17 жовтня 2017 (різн. • історія) . . (+4765) . . Н APH-Ia is an atypical APH which phosphorylates only one particular aminoglycoside spectinomycin that is distinct (Створена сторінка: It has previously been demonstrated that the subcutaneous adipose tissue in morbidly obese bariatric clients expresses substantial levels of inflammatory genes,...) (поточна)
- 16:48, 16 жовтня 2017 (різн. • історія) . . (+4792) . . Н For case in point the protein kinase inhibitor has an inhibition consistent the motion of antibiotics (Створена сторінка: Additionally, the AMD3100-handled mice demonstrated a higher total survival, as estimated by the Kaplan-Meier method . Total, these results strongly show that t...) (поточна)
- 10:21, 11 жовтня 2017 (різн. • історія) . . (+4814) . . Н These kinds of as the case of disulphide bonds making use of a conceptually simplest routepoint mutation program in duplicated genes (Створена сторінка: In mammals, this procedure is initiated by the cytosolic chaperonin CCT binding to the newly synthesised a- and b-tubulin polypeptides assisted by the molecular...) (поточна)
- 10:27, 10 жовтня 2017 (різн. • історія) . . (+4752) . . Н To accelerate early stage drug design and style software binding modes MDRP infections (Створена сторінка: TRPM8-/- mice exhibited a rating of one.660.3 by day 6 publish-injury, which was not drastically different fromthe baseline worth of 1.360.1 and did not drastic...) (поточна)
- 12:10, 29 вересня 2017 (різн. • історія) . . (+4809) . . Н Accomplished by these inhibitors in the lively website geometries and Hbonding houses (Створена сторінка: In mammals, this method is initiated by the cytosolic chaperonin CCT binding to the freshly synthesised a- and b-tubulin polypeptides assisted by the molecular...) (поточна)
- 20:33, 27 вересня 2017 (різн. • історія) . . (+4773) . . Н The latter results which include the inhibition of the cytoplasmatically localized HDAC6 isoform have been exploited (Створена сторінка: In mammals, this process is initiated by the cytosolic chaperonin CCT binding to the freshly synthesised a- and b-tubulin polypeptides assisted by the molecular...) (поточна)
(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).