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- An important component of the ERAD pathway is EDEM 1, a mannosidase-like chaperone that regulates the extraction of misfolded polypeptide chains from calnexin cycle and sends them back to the cytosol for proteasomal degradation (18:58, 3 січня 2017)
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- Six out of seven sites were occupied, as seen from the decrease in mobility caused by the ablation of a consensus site in the single mutants shown (22:19, 3 січня 2017)
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- This shows that site s5 is not critical and the probability to be occupied in human tyrosinase is low. Interestingly, s5 is highly conserved and it is never followed by a proline in positon (22:41, 3 січня 2017)
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