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e., incomplete or impaired colonic visualisation due to inadequate bowel preparation, retained stool, untagged fluid, suboptimal distension, metal or movement artifacts; any colonic segments that cannot be adequately evaluated should be indicated). If colonic abnormalities are found, the following information should be reported: (1) Colonic anatomy (normal or abnormal) and features (wall thickening, diverticula, strictures, extrinsic compression, post-surgical variations); and (2) polyps and/or cancer characteristics (size, maximum diameter and two or three-dimensional measurements, density, morphology, mobility, location, infiltration of extracolonic fat)[18,55]. In 2005, the Working Group on Virtual Colonoscopy elaborated a consensus statement, the CT colonography Reporting and Data System, aimed to ensure clarity and consistency and standardize reporting Histone Demethylase inhibitor of colonic and extracolonic findings in CT colonography[101]. This standardized structure firstly distinguishes polyp lesions from colonic masses. A ��polyp�� is defined as a structure with homogeneous soft-tissue attenuation that arises from the colonic mucosa, characterized by fixed LX4211 order point of attachment to the bowel wall and projecting into the colonic lumen. A ��mass�� is defined as any colonic lesion with soft-tissue attenuation, greater than 3 cm in its largest dimension. However, when the presence of cancer is highly suspected, the ESGAR Consensus Group has suggested that the suspected cancer lesions should be designated as such, avoiding the term mass. Colonic lesion should be characterized in morphology (sessile, pedunculated, flat), size and segmental location[75,85,101]. Sessile lesions are characterised by a broad implant base, with width greater than vertical height. Pedunculated lesions peculiar feature is the presence of a separate stalk. ALK Flat lesions demonstrate a plaquelike morphology, with vertical protrusion