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Similarly, the superoxide generation in patients (P?Wnt inhibitor maxillary canine teeth were selected. After root canal instrumentation, the roots were sectioned horizontally and experimental internal resorption cavities were prepared. The root sections were re-approximated with a luting agent and randomly assigned to three groups (n?=?15) to be filled using CLC, vertical condensation and Thermafil, respectively. Assessment of obturation quality in the internal resorptive cavity was performed using a desktop X-ray micro focus computed tomography scanner, and the percentage of gutta-percha (GP), sealer and voiding was calculated for each specimen. Data were statistically analysed using non-parametric tests, with P?AZ191 of the total artificial cavity, and was superior to CLC (63.20?��?16.87%) and Thermafil (59.26?��?18.47%). The mean percentage of voids was 3.75?��?8.31% in the vertical condensation group, 37.09?��?17.13% in the CLC group and 41.06?��?18.60% in the Thermafil group. We conclude that obturation of experimental resorption cavities is significantly better find protocol when using vertical condensation than when using other GP-based techniques. ""1520" "Background and objective:? Only a small proportion of patients with advanced non-small cell lung cancer (NSCLC) have a life expectancy greater than 2?years. The aim of this study was to identify the factors associated with long-term survival of patients with advanced NSCLC. Methods:? Patients who had received chemotherapy for stage IIIb or IV NSCLC that was not amenable to radiotherapy were studied retrospectively. Data were gathered prospectively from a comprehensive database. Long-term survivors (>2?years) were compared with the other patients, with respect to clinical, biological and tumour�Cnode�Cmetastasis criteria. Results:? Data for 245 consecutive patients were collected. Thirty nine patients (15.9%) survived for more than 2?years. Long-term survivors were more likely to have had metastases at fewer sites (P?=?0.008), an absence of bone metastases (P?=?0.01), a performance status (PS) of 0�C1 at first progression of the tumour (P?=?0.002), a tumour that was controlled with first (P?3?months (P?