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Statistical significance was defined as pSelleckchem UMI-77 All statistical analyses were performed using SPSS V.21.0 (SPSS, Chicago, Illinois, USA). Results Patient characteristics Demographics and baseline characteristics are presented in table 2. Two hundred and eighty-nine patients with NSTEACS were included in the study and separated by pathway (n=101 patients in the DAP, n=109 patients in the PLP and n=79 patients in the CP). The mean age was broadly similar across the groups. DAP had a higher percentage of male patients in comparison to the other groups. Aside from a significantly higher frequency of male patients and patients with previous history of hypertension in the DAP, there were no other variables with statistically significant difference between the groups. CYTH4 Table?2 Baseline characteristics Outcome of invasive investigation Ninety-eight (97%) patients in DAP, 105 (96%) patients in PLP and 75 (95%) patients in CP underwent coronary angiography. Seventy-three (74.7%) patients in DAP, 71 (67.7%) patients in PLP and 62 (78.6%) patients in CP underwent PCI. Eight (8.1%) patients in DAP, six (5.7%) patients in PLP and eight (10.4%) patients in CP underwent coronary artery by-pass grafting (CABG). The remaining were treated with medical therapy. A proportion of patients who were treated with medical therapy across three groups included those with angiographically severe triple vessel disease. This group of patients did not undergo PCI or CABG as they were deemed not suitable for either strategy following a discussion at multidisciplinary team meeting Nintedanib purchase and were thought to be best served by medical therapy. Time to coronary angiography The median time from admission to coronary angiography for DAP, PLP and CP was 2.8 (1.5�C9), 16.6 (6�C50) and 60 (33�C116)?hours, respectively (p across three groups. Length of hospital stay The median length of hospital stay was significantly higher in the CP compared to DAP and PLP groups (5 (3�C7) vs 3 (2�C5) and 3(2�C5)?days, respectively; p