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The GCS scores were primarily extracted from the ambulance records. Hematoma volume was measured on the initial head computed tomography (CT) scan using the ABC/2 method [6]. Outcomes on hospital discharge were documented as scores on the modified Rankin scale (mRS), a stroke outcome scale with scores ranging from 0 (no symptoms at all) to 6 (dead). Also, abstracted was the existence of motor deficit (including aphasia) from the initial examination in order to calculate the WFNS scores. All patients with ICH admitted to the Ohio State University Medical Center are managed in accordance with the American Heart Association/American Stroke Association guidelines [7]. A dichotomy was created separating discharge outcomes into good (mRS �� 2) and poor (mRS �� 4). Regression analysis was then performed to confirm association of each scale to good and poor outcome, as well as to Fluvoxamine in-hospital death. Determination coefficients (r2) were calculated Pazopanib to estimate the amount of variance in outcome explained by the scales. Bland�CAltman plot was performed to assess the correlation of mRS to WFNS score and mRS to the ICH score. Finally, receiver�Coperator characteristic (ROC) curve was used to plot WFNS and ICH scores each in relation to in-hospital mortality and poor outcome. We estimated accuracy by calculating the area under the curves (AUC). A p value of �� 0.05 was considered significant. Minitab? 17 (Minitab Inc., State College, Pennsylvania) and JMP? (Statistical Discovery / SAS, Cary, North Carolina) software were used for statistical analysis. RESULTS A total of 128 patients with an average age of 70.7 �� 13.6 were included in our study. In-hospital mortality rate was 34.4%. Table 1 shows the characteristics of this cohort in more detail. Table 1 Characteristics of the study cohort. SD = standard deviation, ICH = intracerebral hemorrhage, IVH I-BET-762 research buy = intraventricular hemorrhage, mRS = modified Rankin Scale In linear regression with in-hospital death as the dependent variable, the r2 for WFNS was 0.51 and 0.49 for the ICH score, suggesting equal approximation of variance between the two scales. For poor outcome, r2 values for the WFNS and the ICH score were 0.55 and 0.47, respectively. Bland�CAltman plots showed correlation of 0.80 between WFNS and mRS (p