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There were three patients with episodes that lasted Cilengitide that may induce coagulopathy. Temperatures less than 34��C and serum ionized calcium concentrations less than 0.9?mmol��l?1 have been identified as significant (14). While 10 patients were hypothermic at some point by the above criterion, our analysis did not find an association with increased blood loss. The ability to effectively warm these patients from a temperature nadir that often occurs following anesthetic induction and surgical preparation may explain the lack of association between nadir temperatures and blood loss. Intraoperative ionized calcium and potassium values were derived from arterial blood gas determinations. Sixteen patients had one learn more instance of significant hypocalcemia (Everolimus cell line calcium coupled with high potassium could have been present during hypotensive episodes, but we cannot place these measurements in time with the hypotension. Children with craniofacial deformities associated with a named craniosynostosis syndrome often require multiple reconstructive surgeries. In this review, we did not find a difference between children with and without a named craniosynostosis syndrome in terms of BVL, incidence of intraoperative hypotension, and incidence of intraoperative metabolic acidosis. There was no difference in BVL in children undergoing primary and secondary craniofacial procedures. In our analysis, a dilution of the effect of a secondary operation may have occurred, because some secondary procedures involved the posterior vault following previous anterior vault surgery. While technically fitting the definition of a reoperation, these children did not have procedures involving surgical dissection through previously operated cranial regions.