Unsatisfying Myth Around Quinapyramine Unveiled

Although it mostly spreads to the lungs, brain, bones, lymph check details nodes, and adrenal glands, it can involve almost all organs and tissues of the body. Although metastatic pancreatic involvement is a common finding of autopsy series in SCLC, metastasis-induced acute pancreatitis (MIAP) is very rare [2�C4]. Here we reported a 50-year-old woman with SCLC who was admitted for attacks of acute pancreatitis and was diagnosed with MIAP. 2. Case Report The medical work-up of a 50-year-old female patient who applied for chronic cough revealed a mass in the right lung. She had a 40-year pack smoking history and no history of alcohol abuse. Bronchoscopy showed an occlusive mass in the lateral segment bronchus of the right middle lobe and 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) demonstrated a primary mass distal to the bronchus of the right middle lobe and hypermetabolic enlarged lymph nodes in the right lower and upper paratracheal region and the right supraclavicular region (Figures 1(a) and 1(b)). Bronchoscopic biopsy from the mass confirmed small cell carcinoma (Figures 1(c) and 1(d)). Patient's cranial magnetic resonance imaging (MRI) showed no Quinapyramine metastasis, and then she was diagnosed with limited-stage SCLC and started cisplatin-etoposide concurrently with radiotherapy. Treatment was completed without major side effects and a PET-CT was performed after a month, which showed a full metabolic response to the chemoradiotherapy; during follow-up she was provided with prophylactic cranial radiation. The patient was admitted four months after completion of treatment for abdominal pain. The patient reported that she was hospitalized learn more for diagnosis of acute pancreatitis for five days at an outside center two weeks ago; her complaints and amylase level which was initially high were regressed and improved after supportive therapy; however her abdominal pain progressively increased in the last two days. In the physical examination, she had localized pain in the epigastric and periumbilical area; the patient expressed that she felt the pain mostly on the back and lower back. Eastern Cooperative Oncology Group Performance Status (ECOG-PS) was 1 and there was no clinical finding of acute abdomen. The laboratory tests showed a mild leukocytosis and hyperamylasemia (780?U/L) with moderately high C-reactive protein. The patient's history involved no alcohol intake and cholelithiasis, and abdominal computed tomography (CT) demonstrated three metastatic lesions of 0.5�C1?cm in diameter in the liver, nodular metastatic thickening in the right adrenal, and diffuse enlargement of the pancreas, and pancreatic ductus became slightly apparent. In addition to metastatic lesions described on abdominal CT, PET-CT showed abnormal focal FDG uptake in the neck and tail of pancreas with diffusely increased FDG uptake (Figure 2(a)).