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Ethical approval The parents of students were informed; their written consent to the study was taken. The ethical committee approval for the study was received from the local ethics committee, and then permission was obtained from Provincial Directorate of PCI-32765 mw National Education. Statistical analysis While evaluating the data obtained from the study, the SPSS 15.0 for Windows (Chicago-USA) was used. Descriptive statistical methods were given in numbers and percentages for categorical variables and as mean �� standard deviation or median (minimum-maximum) for continuous variables. The conformity of data to a normal distribution was analyzed using Kolmogorov�CSimirnov test. Chi-square test was used to analyze and compare discrete variables. The statistical significance was accepted as P Thalidomide group of 2314 students was determined as 9.21 �� 2.08. From the study group, 48.5% (n = 1123) were male, 51.5% (n = 1191) were female. While general EN prevalence was 9.9% (n = 230), the prevalence of EN and ED together was found out as 2.8% (n = 64). When it is evaluated regarding genders, EN prevalence was determined as 10.7% PARP inhibitor (n = 120) for males and 9.2% (n = 110) for females. The condition of students when they had EN, was evaluated, it was found that 58.7% (n = 135) of them had this problem once a week, 10.4% (n = 24) twice a week, 11.7% (n = 27) 3�C4 times a week, and 19.1% (n = 44) had it every day. Students having both EN and ED were evaluated; it was detected that 71.9% (n = 46) had this problem once a week, 10.9% (n = 7) twice a week, 4.7% (n = 3) 3�C4 times a week, and 12.5% (n = 8) had it every day. From the students in EN (+) group, 52.2% (n = 120) were male, while 48.1% (n = 1003) of EN (?) group were (P = 0.244). Students were divided into three groups; as Group I, of 6�C8 years old (n = 958), Group II, of 9�C11 years old (n = 1014), and Group III, of 12�C14 years old (n = 342). The percentage of students from Group I of EN (+) group was 58.7% (n = 135) while the rate of Group I of EN (?) group was 39.5% (n = 823) (P