An Unbiased Review Of CAL-101

01, rHev b 8, rHev b 9, rHev b 11 were measured by means of ImmunoCAP Phadia System (Phadia, Uppsala, Sweden). ImmunoCAP ISAC test (Phadia, Uppsala, Sweden) was performed with Afatinib solubility dmso 103 molecules including allergens of latex (rHev b 1, rHev b 3, rHev b 5, rHev b 6, rHev b 8), kiwi (nAct d 1, nAct d 2, nAct d 5, nAct d 8), celery (rApi g 1), carrot (rDau c 1), apple (rMal d 1), peach (rPru p 1, nPru p 3), peanut (nAra h 1, nAra h 2, nAra h 3, nAra h 8), hazelnut (rCor a 1.0401, rCor a 8, nCor a 9), pineapple (nAna c 2) etc. The results were expressed in ISAC standardized units (ISU) as well as in classes: class 0 �C 15 ISU. All the participants gave written informed consent before the tests. The protocol was approved by the Independent Bioethics Committee of Medical University of Gdansk. Statistical analysis In statistical analysis, ��2 test with Yates�� correction was applied for comparison of qualitative variables between the study groups. Value of p Selleck CAL101 an anaphylactic shock was documented. Fourteen of these patients reported also reactions to certain food allergens, mostly to banana, kiwi fruit, apple, walnut and hazelnut (Table 2). In group B, food allergy was reported by 16 patients with hazelnut and walnut as the most common allergens. Table 2 Prevalence of positive skin prick tests (SPT) and specific IgE (sIgE) to latex (k82) and food allergens in the study groups Histories of food allergy were partly confirmed by skin prick tests. Their sensitivity was between 27% and 63% with relatively high values for celery (63%), banana (50%) and hazelnut (50%). Their specificity was the highest for banana (87%), walnut (87%), and hazelnut (86%). In contrast, no true positive results were obtained for carrot, Sitaxentan paprika and apple. The number of positive SPTs was significantly higher in patients with clinical symptoms of latex allergy (group A) compared to patients with other allergic conditions (group B) (p = 0.0086). Such differences were not observed in results of sIgE. The sensitivity of their determination was 9�C43% and specificity �C 88�C98%. The highest values were obtained for walnut, kiwi fruit and potato (93�C98%). Sensitization to latex was found by means of SPTs in 13 cases from group A (33.3%) and 3 cases from group B (7.3%). SIgE against latex was revealed in 7 patients from group A (17.9%) and 5 from group B. As far as recombined allergens are concerned, antibodies against Hev b 6.02 and Hev b 8 were most often found (Table 3).