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X divides the distance VT into two equal halves. z is a line perpendicular to t through X. z meets with a at point Y. l is the intersection of the alveolar crest with p, 2 is the intersection of the alveolar crest with r, and 3 the intersection of the alveolar crest with z. This design divides the maxilla into two anterior and two posterior parts. In the anterior region, the experimental area is outlined by the area S12U and the reference area by the area SP'R'U. In the posterior region, the experimental area is V23X and the reference area is VR'YX. Anatomical and reference areas on the right and left sides were pooled, and a ratio (R) for the anterior and posterior bone area was calculated as follows: R?=?experimental/reference area. The anterior and posterior maxillary residual ridge tuclazepam resorption was calculated by subtracting R at T0 from R at T5. A negative difference indicated bone resorption, and a positive difference indicated bone apposition [14]. The area difference (which represents bone resorption along the entire ridge length) was estimated by multiplying the average initial area with the value of the change in R. Then, approximate Microbiology inhibitor changes in height could be calculated by dividing the change in bone area by the average length of the (anterior and posterior) maxillary ridge [15]. Radiographic measurements were made by one caliberated examiner (A.T.M) blinded to treatment groups. All data were analysed with SPSS program version 18 Statistical Packages for Social Science6. The interexaminer correlation XAV-939 clinical trial coefficient was measured for clinical complications using reliability analysis scale (alpha). Freidman's test was used to compare clinical findings between observation times followed by Wilcoxon signed�Crank test for pairwise testing within groups. The maxillary bone ratios (R) were compared between observation times with paired sample t-test. Differences in clinical findings between the two groups were analysed with Mann�CWhitney test. The differences in (R) between groups and between sites (anterior and posterior) were analysed with independent samples t-test. A multiple linear regression analysis was also performed to test whether there was a relationship between R and potential confounding factors: attachment type (group), ridge location (anterior/posterior), maxillary denture relining times, mandibular overdenture relining times and flabby ridge frequency. Probability is significant if