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Actual studies on the products of conception, living, or dead (aborted material) of these couples essential for understanding of process of selective elimination of the alleles. Methods: Of 124 spontaneous abortions occurring during the first 16 weeks of gestation, simultaneous karyotyping and ABO blood grouping of 148 of the parents was carried out. In 80 of the 124 chromosome-analyzed SNS032 aborted foeti, the ABO blood groups of the foeti were determined by the mixed cell agglutinating reaction in fetal tissue. Results: The results of the ABO blood grouping were compared with that of 100 newborns along with their parents (181) from the same area. Among aborted foeti with normal karyotype, a significantly higher (P Enol of newborns (P phosphatase inhibitor library By using mutant strains in metabolic genes from the PHA and tricarboxylic acid (TCA) cycles, we have demonstrated that the co-feeding effect is independent of PHA accumulation, but driven on active glyoxylate shunt and Entner�CDoudoroff (ED) routes. These findings suggested that the effect of octanoate on glycerol metabolism could rely, either on a global activation of the cell energy state, or on the generation of specific metabolites or cofactors needed for the activation of glycerol metabolism. Our results addressed GlpR as the key factor controlling the efficient utilization of glycerol as growth precursor in P.?putida KT2440. Accordingly, a glpR knockout mutant of P.?putida KT2440 showed an elimination of the lag-phase when cultured on glycerol in the absence of co-feeder. Besides, the production of PHA in this strain was increased near twofold, resulting in a higher final yield in terms of PHA accumulation.