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1996a). In this study, comparison of the change in femoral vascular conductance in response to high throughput screening the neck pressure between the exercised and the rested leg was used as a proxy for assessing whether sympathetic neurovascular transduction was altered in the exercised limb. Statistical analysis Preliminary analyses indicated no effect of sex on any outcome variable, so all subsequent analyses were performed with men and women combined as a single group. Variables were analyzed by mixed-model repeated-measures ANOVA with a priori contrasts of preexercise versus postexercise (SAS v9.2; SAS Institute, Inc., Cary, NC). When interaction effects (e.g., leg vs. time) were P?Idelalisib beats per min and mean arterial pressure was 101?��?1?mmHg. Preexercise versus postexercise hemodynamics Heart rate, arterial pressure, femoral blood flow, and femoral vascular conductance before and after exercise are presented in Table?Table2.2. There were no changes in heart rate (P?=?0.90) or mean arterial pressure (P?=?0.39) from before to after exercise. Femoral blood flow in the exercised leg was elevated by 65?��?19% following exercise (P?Ficain sensitivity before and after exercise. Postexercise cardiovagal baroreflex sensitivity was increased ?23% relative to preexercise and had not recovered at 60?min (P?