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Routine items included gender, postcode, date of birth and age, ethnicity, occupational status, exemption from prescription costs, type of NRT prescribed, clinic visits and self-reported abstinence at 4 weeks. NRT-related adverse events and withdrawal symptoms RecBCD were collected from all clients during the following weeks of the cessation attempt. The routine items and dependence data were collected at the start of the quit attempt, while the data on NRT-related adverse events and withdrawal symptoms were collected six times (weeks 1, 2, 3, 4, 6 and 12). A six-item nicotine dependence measure [30] (the Fagerstr?m Test for Nicotine Dependence��Smokeless), eight-item withdrawal symptom measure [31] (the Minnesota Nicotine Withdrawal Scale) and 12-item adverse events related to NRT use measure (generated from an evidence review [32]) were used. This latter measure included one item seeking reports of oral discomfort, tooth pain and/or throat irritation. Satisfaction with the cessation process was measured using a NHS SSS Client Satisfaction Questionnaire [33]. A subsample of participants was selected randomly in proportion to recruitment numbers in each location. Those selected were interviewed by telephone, using the appropriate community language. All data, appropriately anonymized, were transferred to Queen Mary University of London (QMUL) for data cleaning and analysis. The continuous variables were grouped into categories as appropriate. According to variable distribution, responses Antidiabetic Compound Library research buy were manipulated operationally into two or three categories for statistical analysis according Crenolanib cost to the distribution of values around the mean or median or as reported in the literature. Overall dependence scores were calculated from individual participant's responses to questions with a range of 0 (least dependent) to 10 (most dependent). Participants who were lost to follow-up were assigned ��not quit�� status. Descriptive statistics for individual variables were performed initially. Cross-tabulation statistics were performed comparing different categorical variables. Variables were categorized around the median value for dependence scores, daily smokeless tobacco intakes, initial withdrawal symptoms and initial NRT-related adverse events. Relative risk for cessation differences between BS alone and BS and NRT together was estimated. Binary logistic regression models were developed using backward stepwise elimination and the log-likelihood ratio test with client abstinence as the dependent variable. Those independent variables with significance values up to 0.20 (P?
