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17 Parametric data were represented as mean with standard deviation, whereas non-parametric data (i.e. ISS, GCS, TCDB and GOS) are shown as frequencies or median with interquartile range. Median with interquartile range was used for bar graphs. Oxygenase Parametric data were analysed by a Student's t-test for 2-group comparison. Chi-square or Mann�CWhitney U tests were used to perform 2-group comparisons for non-parametric variables. *P?Dactolisib cell line younger and had higher ISS values when compared to single paramedic EMS-treated patients. There were no differences in the prehospital incidence of disturbed pupillary response or hypoxia among groups, whereas the number of patients with prehospital hypotension was higher in the P-HEMS group (20%) than in the EMS group (10%; P?=?0.04). The TCDB CT classification was similar in both groups. The overall prehospital run time was 74?��?54?min. There was a difference in prehospital run time between the urban trauma region (54?��?30?min) and the rural trauma regions (80?��?59?min; P?Selleck MK0683 In total, 75% of all patients were endotracheally intubated in the prehospital phase. The number of endotracheally intubated patients that arrived within 60?min after the emergency call (43%) was lower than the number of non-intubated patients (60%). The percentage of prehospital endotracheal intubations was significantly higher in the P-HEMS group (88%) compared to the EMS group (35%; P?