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Among these variables, indicators for prior bleeding and MI were updated for each successive logistic regression model; other variables are measured at baseline. Off-label stent status is an indicator for off-label use of drug-eluting stents that occurred when the stent was implanted outside of Food and Drug Administration-approved clinical scenarios. GABA receptor activation Additional details on the variables for this analysis are available at http://www.ncdr.com/WebNCDR/NCDRDocuments/datadictdefsonlyv30.pdf. There were 6447 patients with no missing data for covariates included in the analyses. SWs were then calculated according to the formulas in the Statistical Methods section for each individual on each day of the follow-up period until either the subject was censored or died. Regardless of endpoints, we used the daily SWs to examine the sample sizes (Table 1) and covariates balance at three arbitrarily chosen time points: day 1, 180, and 360 out of 540 days after hospital discharge (Table 2, Table 3?and?Table 4). Because SW-adjusted Kaplan-Meier estimates in equation (2) and modified log-rank and Wilcoxon tests (see Appendix in Supplemental Materials at: doi:10.1016/j.jval.2011.07.010) for an endpoint depend on only the SWs on days with the specific endpoint event, different SWs are applied 740 Y-P cost for each distinct endpoint and are re-estimated each time an endpoint occurs. Table 1 shows the sample sizes in the original and weighted data sets at day 1, 180, and 360 out of 540 days after hospital discharge. These results demonstrate that the use of stabilized weights preserves the original sample size and thus the use of SWs would not be expected to inflate type I error rates ALG1 in relevant statistical hypothesis tests including the modified log-rank and Wilcoxon tests for comparing survival data of two groups. SW weightings improved covariate balance in analyzing the clopidogrel use data. During the 540 days of follow-up, in the original cohort the mean number of unbalanced covariates (statistically significant based on P