Background Behind The Temozolomide Accomplishments
6), and 28 adults (12 females, Mage = 27.5 years; SD = 0.2). All children were recruited from the Fondazione Sacro Cuore primary school in Livorno, Italy. Adult participants were recruited from the University of Pisa, Italy. Design and procedure Participants were presented with a computerized version of the Twenty Question game similar to the one used in Study 1 and randomly assigned to one of two conditions: the basic-level or subordinate-level condition. They played the same experimental condition twice, once with objects from the animal domain and once with objects from the profession domain (see Appendix 1 in Supplementary Material). The order in which the domains were presented was randomized. Participants could ask only three questions for each game: Across three rounds, they could select and click from among a set of six options displayed as buttons on the screen. The six options always included two constraint-seeking questions (e.g., ��Does it live in the water?��)��one with higher and one with lower information gain, when possible��two pseudoconstraint-seeking questions (e.g., ��Is it a flat kind of fish?��), and two hypothesis-scanning questions (e.g., ��Is it the sole?��). Upon selection of a question, the computer automatically darkened the buttons corresponding to the objects the question had ruled out. After participants had asked the third question, they had to guess the object the computer had randomly chosen by selecting one of the remaining objects. Children who guessed the right object in both games received a box of colored pencils. Adults who guessed both objects were entered in a lottery the winner of which was awarded a 20-Euro Amazon gift card. Results We ran a repeated-measures ANOVA with the order of the questions (i.e., whether a question was asked in the first, second, or third round) and domain as within-subject Temozolomide factors, and inclusiveness and age group as between-subjects variables for all dependent measures. As in Study 2, when presenting the results for the type of questions selected, we report only the analysis of the proportion of constraint-seeking questions, for the sake of brevity. All main effects and interactions were tested but we report only significant effects. Information gain We found no effect of the order of questions (p = 0.13) or inclusiveness (p = 0.55) but a main effect of age group, F(2, 82) = 18.6, p