All Formula Linked To RRAD
Endosteal and callus along the osteotomy line was also still found in G4, but the cis-cortex appeared smoother compared to G1 and more irregular compared to G3. Bridging was achieved also in G5 in both cortices with woven bone. From all groups the periosteal callus was largest at the trans- and cis-cortex and endosteal callus was present in 5/6 specimens. Although the periosteal callus at the trans-cortex was smaller compared to the 6?weeks group, it RRAD still was irregular at its surface and seemed more active compared to all other groups. Little fragments of the tip of the bone fragments at the trans-and cis-cortex were found mostly in G1 and G2, but not in the other groups. Remodelling of fragment ends was prominent in all groups. However, in G1 and G2 the most intensive remodelling was seen at the cis-cortex and this between the first screw close to the fragment tip and the head of the lag screw. Results of histomorphometry confirmed the impression obtained by the qualitative evaluation of ground sections. As indicated in Table 3 percentage of new bone matrix increased in all but one group (G3) between 6 and 12?weeks. The fraction of new bone matrix included selleckchem periosteal and endosteal callus as well as new bone tissue deposited between the bone fragments. In G5 was the highest percentage found at 6 and at 12?weeks, which was significantly different to G2 and G3 (p?��?0.003) at 12?weeks. The old matrix was similar between the time points with only G2 showing a tendency for decreased see more percentage. Values for granulation tissue were variable. G2 and G3 showed the highest values due to the fact that the endosteal callus was already diminished or absent due to remodelling and advanced bone healing. A significant negative correlation between old and new matrix and granulation tissue was found in all groups (p?