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This approach takes into account the uniqueness of patients by including individual patient characteristics and specific disease combinations in the treatment outcome determination. It binedaline gives PTs the opportunity to customize medical treatments for individual patients. Hence, putting existing information to a new and systematic use may help guide PT through the complex process of managing patients with multimorbidity. Author Contributions All authors contributed to his work. The ideas of the manuscript were discussed with the whole project team. SD, IM, and RB wrote the manuscript. JT commented on the manuscript and gave conceptual advice at the final stage. Conflict of Interest Statement We declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. This manuscript has not been previously published and is not under consideration in the same or substantially similar form in any other peer-reviewed media. We declare that we have no significant competing financial, professional, or personal interests that might have influenced the performance or presentation of the work described in this manuscript. All authors listed have contributed sufficiently to the project to be included as authors. Acknowledgments Funding: This study was made possible Dabrafenib price by a NWO Graduate Programme grant (grant number 022.003.036). Abbreviations COPD, chronic obstructive pulmonary disease; IC, intermittent claudication; PT, physical therapist; Spad, symptomatic peripheral arterial disease.""According to the World Health Organization (WHO) reports, chronic illnesses contribute to 60% of death worldwide (1). Being a major chronic disease; type II diabetes (T2DM) seems to be one of the leading causes of mortality and of public health burden (2). The increasing incidence of diabetes worldwide has been highly linked to the westernized dietary patterns, physical inactivity, and increasing rates of obesity and metabolic syndrome. Over the past few years, there has been a great effort to find more study the relationship between dietary patterns and human health. Interestingly, adherence to a healthy life style was strongly associated with reduction in the risk of chronic illnesses (83% reduction in coronary artery disease and 91% reduction in diabetes mellitus in females) (3). Moreover, PREDIMED �C Reus study nutrition intervention trial showed that adherence to Mediterranean diet was associated with 52% reduction of diabetes mellitus incidence (4). The American Diabetes Association (ADA) does not recommend a specific diet over another for the diabetic patients. However, it clearly states that the total amount of fat should represent 25�C35%, and saturated fat of