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, 2006]. This model focuses on theories in organizational behavioral science. In addition, debriefing theory is grounded in the adult theories of Knowles et al. [1998] and Kolb [1984]. These focus on active and contextually specific based learning in which adult learners have different preferred styles of maximal learning. An anonymous post-evaluation survey was administered after debriefing. Results of the behavioral Olaparib checklist and post-evaluation survey were analyzed using SPSS statistical software (Chicago, IL). Items on the behavioral checklist were categorized into five sections including the genetics of DS, pregnancy options, and three age ranges (infancy/early development, school aged, and adolescent/young adult). Results were compared using a chi-squared test. Demographic data were compared using an unpaired t-test. Average scores with Trametinib manufacturer standard deviations are presented along with 95% confidence intervals of the difference. Results of the evaluations are summarized and themes of the open-ended sections were tabulated. All quantitative statistical tests were two-tailed and a P?FKBPL the frequency of different medical topics discussed during the simulation. There was a trend towards participants being more likely to discuss issues the child could have while an infant/toddler rather than issues that could emerge as the child with DS transitions to adulthood and end of life. Open-ended responses on the post-evaluation survey revealed that participants felt the simulation was a useful learning experience. Sample verbatim written comments are listed below and are related to the following question: ��Do you believe today's simulation was an effective way to explore and improve your counseling abilities?�� Yes. Counseling is a large part of the clinical role of a medical geneticist.