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Poor oral hygiene is reported to accelerate the bone loss observed around endosteal implants. According to the results obtained from this study, more crestal bone loss was observed with 10 mm implants when compared to the 13 mm implants. This might be LY294002 due to the better primary stability obtained with longer implants (13 mm) when compared to the shorter ones (10 mm) due to increase in the surface area of long implants and thus contributing to better anchorage and bone-implant integration. According to the results obtained from this study, more crestal bone loss was observed in females as compared with males. In this study, the mean crestal bone loss of 0.5531 mm on mesial and 0.5037 on distal aspect of implant are within the success criteria of implant (mean crestal bone loss Lapatinib in vitro was 0.5531 mm on mesial and 0.5037 mm on distal aspect of implant There were no statistically significant differences between the marginal bone loss on mesial compared with the distal aspect of implant after 6 months of implant placement. Thus, the bone loss on mesial and distal aspects of implants was found to be same after a period of 6 months The mean marginal bone loss for 13 mm implants was 0.485 mm on mesial and 0.3475 mm on distal aspect of implant. Whereas, the mean marginal bone loss for 10 mm implants was 0.6212 mm on mesial and 0.66 mm on distal aspect of implant. Thus, in this study, the bone loss was found to be same in both 13 mm and 10 mm implants on the mesial aspect of implant whereas on distal aspect, it was more in 10 mm implants when compared with 13 mm implants The mean marginal bone loss for 3.5 mm implants was 0.5387 S6 Kinase mm on mesial and 0.4512 mm on distal aspect of implant. Whereas, the mean marginal bone loss for 4.3 mm implants was 0.5675 mm on mesial and 0.5562 mm on distal aspect of implant. Thus, in this study, the bone loss was found to be same in both 3.5 mm and 4.3 mm diameter implants on both mesial and distal aspects of implants The mean marginal bone loss for implants placed in maxilla was 0.601 mm on mesial and 0.481 mm on distal aspect of implant. Whereas, the mean marginal bone loss for implants placed in mandible was 0.4733 mm on mesial and 0.5417 mm on distal aspect of implant. Thus, in this study, the bone loss was found to be same in both maxilla as well as mandible on both mesial and distal aspects of implants The mean marginal bone loss for implants placed in males was 0.4554 mm on mesial and 0.4264 mm on distal aspect of implant.