The Most Unusual BGB324 Saga
A clinically ��stable�� group comprised those patients who arrived without persistent haemodynamic derangement or peritonitis and who underwent further CT evaluation, and an additional subgroup that was investigated with x-ray and ultrasound in the emergency department and who subsequently underwent diagnostic laparoscopy after a planned observation period. Amongst patients arriving clinically ��stable�� was a subset with CT findings leading to emergent surgery. This group combined with the ��unstable�� group to form an ��emergent surgery�� population. All other clinically ��stable�� patients were identified as undergoing NOM. Once identified from the registry, this population was verified by chart review. Demographics, admission physiology, injury patterns, operative repairs and outcomes were described for the total population, and the ��emergent surgery�� and ��clinically stable�� subgroups were compared. The ��clinically stable�� group Ramoplanin was examined, comparing patients undergoing successful vs. unsuccessful NOM. BGB324 solubility dmso Failure of NOM was defined broadly, as need for laparotomy for any reason, but also specifically, as the need for a splenic operative procedure. The entire population was then examined by grade of splenic injury. For those failing NOM, time to failure, transfusion requirements, splenic procedures performed, and associated repair of a solid organ, DI or HVI were described by splenic grade of injury. Finally, the incidence of all complications and duration of follow-up was described for patients undergoing NOM. Statistical analyses were performed using SPSS for Windows, version 17 (Chicago, IL). Continuous variables were occasionally dichotomised using relevant cut-points: age (��55 vs. 8); and Injury Severity Score (ISS), (��25 vs. SCH727965 nmr were reported as a percentage of the total population. Proportions were compared utilizing chi-square tests with Yate's correction. Differences between continuous variables were assessed using 2-tailed t tests. A p value was considered significant if
