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Retrospective chart analysis of 137 patients who underwent SDAF/SARS at a single institution. Patients were categorized as being at risk of renal damage when the maximum detrusor pressure was >40?cmH2O or detrusor compliance was Trametinib mw of symptomatic UTI also decreased significantly (P?Olaparib research buy surgical revision were observed. Defects of the stimulator cables or the receiver plate were the most common events (n?=?38). The retrospective design pertains to the limitations of the study. Sacral deafferentation and SARS are an effective treatment option for refractory NLUTD in patients with complete SCI, despite a substantial long-term complication rate. Neurourol. Urodynam. 33:1202�C1206, 2014. ? 2013 Wiley Periodicals, Inc. ""To investigate the functional outcome after supratrigonal cystectomy and augmentation ileocystoplasty in adult patients with refractory neurogenic lower urinary tract dysfunction (NLUTD). Retrospective follow-up investigation in a single spinal FKBPL cord injury rehabilitation center. In 29 patients, urodynamic data before and after supratrigonal cystectomy and augmentation ileocystoplasty, clinical outcome and post-operative complications were evaluated. The median age of the 29 patients at the time of surgery was 31 years, a median 14 years after NLUTD had occurred. At the last follow-up visit (median 2.4, range 0.4�C9.0 years post-operatively), 20/29 patients (69%) were continent compared to 2/29 pre-operatively (P?=?0.001). Furthermore, 16 patients required no or less detrusor relaxation therapy after augmentation ileocystoplasty. Augmentation cystoplasty resulted in a significant (P?=?0.001) increase in the median bladder capacity (from 240?ml to 500?ml) and compliance (from 13?ml/cm H2O to 50?ml/cm H2O). The median maximum detrusor pressure had decreased significantly (P?=?0.001) from 38?cm H2O to 15?cm H2O. Significantly (P?=?0.001) fewer patients presented with a risk for renal damage (1 vs. 15 with maximum detrusor pressure >40?cm H2O and 1 vs. 12 with detrusor compliance