15 BAY-61-3606 Interaction Ideas

The CMR-TSI was higher in the ICM group than in the DCM +MWHE group (p Thymidine kinase median follow-up time 1,038 days [2.84 years]), total mortality was 10 of 20 (50%) in DCM +MWHE and 5 of 77 (6.5%) in DCM ?MWHE. Cardiovascular mortality was 9 of 20 (45%) and 2 of 77 (2.6%) in the DCM +MWHE and DCM ?MWHE groups, respectively. In the ICM group, total mortality was 53 of 161 (31.8%) and cardiovascular mortality was 49 of 161 (30.4%). Among patients with DCM, +MWHE predicted cardiovascular mortality (hazard ratio [HR]: 18.1; p BAY-61-3606 price hazards analyses, scar burden did not emerge as a predictor of total mortality (HR: 0.99; 95% CI: 0.87 to 1.14; p = 0.94) or cardiovascular mortality (HR: 1.02; 95% CI: 0.89 to 1.16; p = 0.82). Of the 60 cardiovascular deaths, 46 were due to pump failure (DCM +MWHE 6 of 20 [30%]; DCM ?MWHE 2 of 77 [2.6%]; ICM 38 of 161 [23.6%]). In univariate analyses comprising the DCM and ICM subgroups, both ICM (HR: 10.5; 95% CI: 2.52 to 43.5; p = 0.0012) and DCM +MWHE (HR: 14.1; 95% CI: 2.85 to 70.0; p = 0.0012) emerged as predictors Q-VD-Oph of death from pump failure. Of the 60 cardiovascular deaths, 14 were sudden cardiac deaths (DCM +MWHE 3 of 20 [15%]; DCM ?MWHE 0 of 77 [0%]; ICM 11 of 161 [6.8%]). In univariate and multivariate analyses comparing with DCM ?MWHE, both DCM +MWHE and ICM significantly improved the Cox regression model using the likelihood ratio test (p = 0.0029), and both DCM +MWHE (HR lower 95% CI: 2.65) and ICM (HR lower 95% CI: 4.54) emerged as predictors of sudden cardiac death. Five patients had unplanned hospitalizations for major arrhythmic events (DCM +MWHE 1 of 20 [5.0%] for atrial fibrillation; DCM ?MWHE 1 of 77 [1.3%]; ICM 1 atrial fibrillation, 1 ventricular tachycardia, and 1 ventricular fibrillation [total 3 of 161 (5.0%)]).