Ospective project registered with clinicaltrials.gov (NCT00963352). Statistical evaluation The

Elderly sufferers are stead-bound and in some cases if some of them were not followed up frequently, they could possibly be tracked and life status ascertained through their identity program eier survival curves for 269 individuals resected number within the official National Population Registry. Death certificates for all deceased individuals had been out there by way of Statistics, Norway.Outcomes Two hundred sixty-nine individuals, 152 (56.five ) women and 117 guys, with a imply age of 71 years (range, 203 years) were studied. Among the hospitals operated male sufferers that had been younger, with a mean of 67 years.Int J Colorectal Dis (2011) 26:1299Surgery The various tumor locations are shown in Table 1. Tumor locations weren't unique involving the hospitals (p=0.059). Appropriate hemicolectomy and sigmoid resection were one of the most common procedures (78.4 ). Locoregional R0 resections for a single tumor location had been done in 264 sufferers, although double resections (n=4) along with a suspected locoregional R1 resection (n=1) were completed in five patients. Pathology There had been no considerable differences in between hospitals relating to TNM stage distribution: 34 sufferers (12.six ) were stage I, 116 sufferers (43.1 ) have been stage II, 93 patients (34.six ) were stage III, and 26 sufferers (9.six ) had been stage IV. The number of lymph nodes harvested for numerous stages were 8.7 (stage I), 10.three (stage II), 10.9 (stage III), and ten.three (stage IV). In 11 sufferers, the pathologist had classified the T category and TNM stage but omitted to specify the amount of lymph nodes present. The mean number in 258 sufferers was ten.three lymph nodes per specimen. Twelve or more lymph nodes were examined in 41.1 (106/258) on the resected specimens. Drastically fewer lymph nodes (p0.001) were harvested at certainly one of the hospitals. Otherwise, the three patient populations had related qualities.Ospective project registered with clinicaltrials.gov (NCT00963352). Statistical analysis The chi-square test was used to evaluate groups with respect to categorical variables and analysis of variance for continuous variables. The following variables had been analysed with respect to survival: hospital, age, gender, location, no of lymph nodes and lymph node ratio (LNR), T stage, and TNM stage. Survival curves have been estimated by the Kaplan eier method [7] and compared applying the logrank test [8]. A number of prognostic elements were analysed with all the Cox proportional hazards model [9] utilizing the SPSS 17 package.Material and strategies Individuals from a national cohort have been operated in 2000, and follow-up was until December 2007, a mean of 7.5 years later. 3 teaching community hospitals, Haraldsplass Deaconal Hospital, Stavanger University Hospital, and Akershus University Hospital contributed sufferers. Surgery All 3 hospitals are teaching community hospitals, and the individuals were operated with an open access by a large variety of surgeons. At that time, extra radical surgery was unusual, and it's fair to assume that radical surgery commonly constituted a moderate mesocolic resection. If metastases had been diagnosed, patients and tumor circumstances have been assessed with regards to feasibility for resection. Follow-up Sufferers ordinarily went to the outpatient clinic each and every third month for the initial two years then each sixth month until five years had passed. Blood tests with carcinoembryonic antigen measurement and ultrasonography of your liver and chest X-ray had been carried out.