G, S. C., J. Chang, B. McCowan, and V. A. Zakian

title= srep18714 Daenen, P. J. Verbelen, K. J. Verstrepen et al., 2010 Flocculation gene variability in industrial brewer's yeast strains. Appl. Microbiol. Biotechnol. 88: 1321--1331. Wapinski, I., A. Pfeffer, N. Friedman, plus a. Regev, 2007 Natural history and evolutionary principles of gene duplication in fungi. Nature 449: 54--61. Wenger, J. W., J. Piotrowski, S. Nagarajan, K. Chiotti, G. Sherlock et al., 2011 Hunger artists: yeast adapted to carbon limitation show trade-offs below carbon sufficiency. PLoS Genet. 7: e1002202. Winzeler, E. A., C. I. Castillo-Davis, G. Oshiro, D. Liang, D. R. Richards et al., 2003 Genetic diversity in yeast assessed with wholegenome oligonucleotide arrays. N/IGF signaling in experimental alcohol-related myopathy. Nutrients 2012, 4, 1058?075. Lang, C.H. genetics 163: 79--89. Zhang, A., K. O. Petrov, E. R. Hyun, Z. Liu, S. A. Gerber et al., 2012 The Tlo proteins are stoichiometric elements of Candida albicans mediator anchored by means of the Med3 subunit. Eukaryot. Cell 11: 874--884. Zhang, A., Z. Liu, and L. C. Myers, 2013 Differential regulation of white-opaque switching by person subunits of Candida albicans mediator. Eukaryot. Cell 12: 1293--1304. Communicating editor: J. HeitmanReal-Time EvolutionGENETICSSupporting Information http:/ /www.genetics.org/lookup/suppl/doi:ten.1534/genetics.115.177451/-/DCReal-Time Evolution of a Subtelomeric Gene Family in Candida albicansMatthew Z. Anderson, Lauren J. Wigen, Laura S. Burrack, and Judith BermanCopyright ?2015 by the Genetics Society of America DOI: ten.1534/genetics.115.AGene conversionTLO TLOBBreak-induced replicationTLO TLOTLOTLOTLOTLOTLOTLOTLOTLOTLO TLORecipient DonorFigure S1 Mechanisms of TLO recombination. Subtelomeric double strand breaks within a Issions, our findings recommend that hospitals could possibly also achieve reductions in chromosome induce repair mechanisms that may possibly occur in unique approaches. Through gene conversion (A), the break is repaired using an ectopic paralogous sequence located at a different subtelomere. Resectioning in the course of repair can result in loss with the native TLO by replacement with the TLO from yet another chromosome. The finish in the broken chromosome is lost for the duration of break induced replication (B), with an ectopic chromosome end serving as a template to restore the missing chromosome finish.2 SIM.Z. Anderson, et al.YJB9929 (passage 380) 1 individualTLO9 TLO8 TLO10 TLO23 individualsYJB9929 (passage 411)Figure S2 Kinetics of recombination events. Sequencing with the YJB9929 population identified recombination on Chr4R amongst passage 380 and 411.G, S. C., J. Chang, B. McCowan, and V. A. Oshiro, D. Liang, D. R. Richards et al., 2003 Genetic diversity in yeast assessed with wholegenome oligonucleotide arrays. Genetics 163: 79--89. Zhang, A., K. O. Petrov, E. R. Hyun, Z. Liu, S. A. Gerber et al., 2012 The Tlo proteins are stoichiometric components of Candida albicans mediator anchored through the Med3 subunit. Eukaryot. Cell 11: 874--884. Zhang, A., Z. Liu, and L. C. Myers, 2013 Differential regulation of white-opaque switching by individual subunits of Candida albicans mediator. Eukaryot. Cell 12: 1293--1304. Communicating editor: J. HeitmanReal-Time EvolutionGENETICSSupporting Information and facts http:/ /www.genetics.org/lookup/suppl/doi:ten.1534/genetics.115.177451/-/DCReal-Time Evolution of a Subtelomeric Gene Family members in Candida albicansMatthew Z. Anderson, Lauren J. Wigen, Laura S. Burrack, and Judith BermanCopyright ?2015 by the Genetics Society of America DOI: ten.1534/genetics.115.AGene conversionTLO TLOBBreak-induced replicationTLO TLOTLOTLOTLOTLOTLOTLOTLOTLOTLO TLORecipient DonorFigure S1 Mechanisms of TLO recombination.