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(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).
- 12:34, 6 вересня 2018 (різн. • історія) . . (+5610) . . Н Calcineurin knockout mice show the inhibition of motor functionsloss of synaptic plasticitylearning and memory (Calcineurin knockout mice show the inhibition of motor functionsloss of synaptic plasticitylearning and memory) (поточна)
- 16:23, 26 серпня 2018 (різн. • історія) . . (+6180) . . Н PKC-a plays a role in regulation of membrane associated signal transduction pathways mediated by Ca homeostasis (PKC-a plays a role in regulation of membrane associated signal transduction pathways mediated by Ca homeostasis) (поточна)
- 13:08, 24 травня 2018 (різн. • історія) . . (+4356) . . Н Several effectors have been identified for Sec4p including Sec15pa member of the octameric exocyst complex (Several effectors have been identified for Sec4p including Sec15pa member of the octameric exocyst complex) (поточна)
- 10:43, 12 квітня 2018 (різн. • історія) . . (+4087) . . Н Four various versions of the binding pocket ended up ready having into diverse tautomers of His25 (Four various versions of the binding pocket ended up ready having into diverse tautomers of His25) (поточна)
- 11:15, 11 квітня 2018 (різн. • історія) . . (+4117) . . Н 4 different versions of the binding pocket had been prepared having into diverse tautomers of His25 (4 different versions of the binding pocket had been prepared having into diverse tautomers of His25) (поточна)
- 20:49, 4 квітня 2018 (різн. • історія) . . (+4067) . . Н This timeframe was considerably shorter than that of cells treated with vintage anti-mitotic drugs this kind of as nocodazole (This timeframe was considerably shorter than that of cells treated with vintage anti-mitotic drugs this kind of as nocodazole) (поточна)
- 12:40, 2 квітня 2018 (різн. • історія) . . (+4497) . . Н The strains carrying considerably less lively SDHs are not compensating for this influence by overexpression of the enzyme (Створена сторінка: At the early premolt, elevated ranges of [https://pixabay.com/en/photos/?q=ecdysteroids ecdysteroids] might stimulate the MIH expression in eyestalk ganglia tha...) (поточна)
- 14:19, 30 березня 2018 (різн. • історія) . . (+4170) . . Н The strains carrying much less energetic SDHs are not compensating for this impact by overexpression of the enzyme (Створена сторінка: Glia-mediated neuroinflammation has extended-been regarded in [http://www.abmole.com/products/tws119.html TWS119 abmole bioscience] Advert pathogenesis. In addi...) (поточна)
- 15:21, 29 березня 2018 (різн. • історія) . . (+4521) . . Н We initial decided the amount of SDH enzyme in mitochondrial preparations for every single of the resistant strains (We initial decided the amount of SDH enzyme in mitochondrial preparations for every single of the resistant strains) (поточна)
- 04:53, 28 березня 2018 (різн. • історія) . . (+4117) . . Н The characterization of much more than mutants enabled the identification of as many as substitution varieties (Створена сторінка: Consequently, inhibition of neuroinflammation is an crucial concentrate on for TGF-β1 prevention and therapy of Advertisement neurodegeneration. Nonetheless,...) (поточна)
- 04:42, 28 березня 2018 (різн. • історія) . . (+4196) . . Н To this subjected to random UV mutagenesis and structurally distinctive carboxamides ended up utilised for choice (Створена сторінка: Glia-mediated neuroinflammation has long-been identified in Advert pathogenesis. In addition, changes in peripheral T cells in Advert clients or in Ad animal mo...) (поточна)
- 18:57, 26 березня 2018 (різн. • історія) . . (+4597) . . Н A current cross resistance study performed with a assortment of novel were selected (Створена сторінка: Little molecule inhibitors are administered orally and are likely to have a a lot shorter 50 %-existence than antibodies. A lot more drastically, antibodies and...) (поточна)
- 15:02, 22 березня 2018 (різн. • історія) . . (+4243) . . Н Utilizing transgenic strains expressing mutated copies of the enzyme SDH subunits we confirmed very lower levels of SDH activity (Створена сторінка: As a result, only 4 compounds were considered for dialogue and further experiments like kinetic and thermodynamic research to characterize these compounds as po...) (поточна)
- 14:48, 22 березня 2018 (різн. • історія) . . (+4657) . . Н A current cross resistance examine performed with a assortment of novel had been picked (A current cross resistance examine performed with a assortment of novel had been picked) (поточна)
- 18:17, 21 березня 2018 (різн. • історія) . . (+4146) . . Н To this subjected to random UV mutagenesis and structurally unique carboxamides had been utilised for selection (Створена сторінка: Glia-mediated neuroinflammation has extended-been recognized in Advert pathogenesis. In addition, changes in peripheral T cells in Ad patients or in Ad animal v...) (поточна)
- 15:58, 19 березня 2018 (різн. • історія) . . (+4248) . . Н The benzofuroxans represented the other big household examined (Створена сторінка: Rising evidence implies that though vast majority of MBs harbor wild-sort p53, the tumor suppressor purpose of p53 is usually impacted by the connected oncogene...) (поточна)
- 14:33, 14 березня 2018 (різн. • історія) . . (+4318) . . Н With the existence of an electrophilic/electron-withdrawing group as benzo-substituent (Створена сторінка: The specific mechanisms by which CFMs impact p21Rac1 and MMP expression are the subjects of our on-going research. In summary, the info offered here convincingl...) (поточна)
- 13:48, 14 березня 2018 (різн. • історія) . . (+4037) . . Н In the same way a phenyl substituent in C4 favors inhibition possibly as an further electron-withdrawing team (In the same way a phenyl substituent in C4 favors inhibition possibly as an further electron-withdrawing team) (поточна)
- 10:56, 12 березня 2018 (різн. • історія) . . (+4176) . . Н There is no one vaccine offered for a human flatworm infection and the pharmacological arsenal (There is no one vaccine offered for a human flatworm infection and the pharmacological arsenal) (поточна)
- 13:35, 9 березня 2018 (різн. • історія) . . (+4298) . . Н There is no solitary vaccine obtainable for a human flatworm an infection and the pharmacological arsenal (Створена сторінка: Rising proof implies that despite the fact that majority of MBs harbor wild-sort p53, the tumor suppressor perform of p53 is typically impacted by the associate...) (поточна)
- 16:55, 7 березня 2018 (різн. • історія) . . (+4373) . . Н Management programs of cystic echinococcosis are based mostly on recurring anthelmintic remedy of canine with praziquantel (Створена сторінка: Third, the availability of technological tools for trustworthy precise translation of the qualified animal or human individual is a crucial prerequisite for an...) (поточна)
- 14:10, 6 березня 2018 (різн. • історія) . . (+5218) . . Н It has extended been thought that the functional consequences of HDACi are mediated by their capability (It has extended been thought that the functional consequences of HDACi are mediated by their capability) (поточна)
- 15:50, 5 березня 2018 (різн. • історія) . . (+5304) . . Н It has prolonged been imagined that the purposeful results of HDACi are mediated by their ability (Створена сторінка: Due to the rapid evolution of hypertensive conditions in our research groups, we could look into only the biological results of the antihypertensive treatment o...) (поточна)
- 17:58, 2 березня 2018 (різн. • історія) . . (+5138) . . Н Our benefits demonstrate that many genes are sheltered from the international histone hyperacetylation induced by HDACi (Створена сторінка: However, in the presence of either Al or Ga, two metals known to make ROS, succinate was also made. The inclusion of catalase prior to the addition of the metal...) (поточна)
- 17:47, 2 березня 2018 (різн. • історія) . . (+5327) . . Н It has lengthy been considered that the purposeful effects of HDACi are mediated by their ability (Створена сторінка: Due to the fast evolution of hypertensive ailments in our review groups, we could examine only the organic consequences of the antihypertensive treatment method...) (поточна)
- 14:16, 28 лютого 2018 (різн. • історія) . . (+5296) . . Н In the doxorubicin dealt with group of our examine Akt of the blend group in contrast to the everolimus-taken care of one (Створена сторінка: Owing to the speedy evolution of hypertensive conditions in our study groups, we could look into only the biological outcomes of the antihypertensive remedy ove...) (поточна)
- 10:45, 26 лютого 2018 (різн. • історія) . . (+5134) . . Н Measurement of the phosphorylation status in the tumor alone confirmed that everolimus resulted in a down regulation of mTOR (Створена сторінка: Nonetheless, in the presence of both Al or Ga, two metals identified to produce ROS, succinate was also made. The inclusion of catalase prior to the addition of...) (поточна)
- 10:34, 26 лютого 2018 (різн. • історія) . . (+5342) . . Н By adhering to activation levels of S6K as potential surrogate markers of tumor response on its phosphorylation position (Створена сторінка: Recently two teams solved the composition of N1L which has striking homology to the Bcl-2 family of antiapoptotic genes. In vitro, the N1L protein inhibits NF-k...) (поточна)
- 13:28, 23 лютого 2018 (різн. • історія) . . (+5278) . . Н In the doxorubicin treated group of our review Akt of the combination group in comparison to the everolimus-treated one (Створена сторінка: Thanks to the rapid evolution of hypertensive illnesses in our research teams, we could investigate only the organic outcomes of the antihypertensive remedy ove...) (поточна)
- 08:25, 14 лютого 2018 (різн. • історія) . . (+5236) . . Н In this phase not only the interaction energies had been regarded as but also the sort of interactions (Створена сторінка: The demonstration of the attachment of a GPI anchor to soluble mesothelin was performed by ELISA assays, tandem mass spectrometry and co-immunoprecipitation. Ce...) (поточна)
- 08:13, 14 лютого 2018 (різн. • історія) . . (+4934) . . Н Individuals residues with greater values were visually inspected in purchase to deduce a protein-protein pharmacophore (Створена сторінка: Tumor-connected macrophages share homes with M2 macrophages, like higher expression of IL10 and mannose receptor , and reduced expression of IL-12 . TAMs consti...) (поточна)
- 09:42, 12 лютого 2018 (різн. • історія) . . (+4905) . . Н Those residues with larger values were visually inspected in get to deduce a protein-protein pharmacophore (Створена сторінка: Tumor-associated macrophages share houses with M2 macrophages, including higher expression of IL10 and mannose [https://pixabay.com/en/photos/?q=receptor recept...) (поточна)
- 08:07, 9 лютого 2018 (різн. • історія) . . (+4866) . . Н These residues with higher values have been visually inspected in purchase to deduce a protein-protein pharmacophore (Створена сторінка: Tumor-associated macrophages share qualities with M2 macrophages, including large expression of IL10 and mannose receptor , and lower expression of IL-twelve ....) (поточна)
- 12:08, 7 лютого 2018 (різн. • історія) . . (+5087) . . Н The function introduced here supports main the HCV capsid protein as a novel target for anti-HCV drug advancement with other HCV proteins (Створена сторінка: The demonstration of the attachment of a GPI anchor to soluble mesothelin was performed by ELISA assays, tandem mass spectrometry and co-immunoprecipitation. Ce...) (поточна)
- 11:57, 7 лютого 2018 (різн. • історія) . . (+5260) . . Н Binding is robust ample to keep core complexes that contains (Створена сторінка: Extensive surgical cytoreduction like peritoneal [http://www.abmole.com/products/torin-1.html Torin 1] stripping and bowel resection had been utilized in sixty...) (поточна)
- 11:07, 6 лютого 2018 (різн. • історія) . . (+5195) . . Н The function presented right here supports main the HCV capsid protein as a novel concentrate on for anti-HCV drug improvement with other HCV proteins (Створена сторінка: The demonstration of the attachment of a GPI [http://www.abmole.com/products/vorinostat.html Vorinostat 149647-78-9] anchor to soluble mesothelin was carried ou...) (поточна)
- 14:48, 5 лютого 2018 (різн. • історія) . . (+5298) . . Н Necdin has an anti-angiogenic function by interacting with HIF-1-alpha and by negatively regulating its activity on VEGF induction (Створена сторінка: Whether or not adjustments observed at the transcript amount are [http://www.abmole.com/products/ve-822.html VE-822] mirrored in adjustments in protein levels n...) (поточна)
- 14:38, 5 лютого 2018 (різн. • історія) . . (+5162) . . Н Importantly our results also present that Necdin can be induced by PyLT in a p53-unbiased way which in a most cancers context (Створена сторінка: Although it is not possible to especially goal CFLARshort transcripts utilizing qRT-PCR, we identified expression of CFLARlong and identified it not to be diffe...) (поточна)
- 13:34, 2 лютого 2018 (різн. • історія) . . (+5321) . . Н Necdin has an anti-angiogenic perform by interacting with HIF-1-alpha and by negatively regulating its action on VEGF induction (Створена сторінка: Whether or not alterations observed at the transcript amount are mirrored in alterations in protein stages call for further investigation. By focusing on transc...) (поточна)
- 13:07, 31 січня 2018 (різн. • історія) . . (+5248) . . Н Cause a reduction in p53 exercise and potentially lead to checkpoint bypass and genomic instability (Створена сторінка: Although exposure to nigericin brought on an early boost in TNFSF13 and FAS receptor [http://www.abmole.com/products/wz4002.html WZ4002 EGFR/HER2 inhibitor] exp...) (поточна)
- 12:55, 31 січня 2018 (різн. • історія) . . (+5256) . . Н Importantly our outcomes also demonstrate that Necdin can be induced by PyLT in a p53-independent manner which in a most cancers context (Створена сторінка: Although it is not achievable to exclusively goal CFLARshort transcripts making use of qRT-PCR, we decided expression of CFLARlong and located it not to be diff...) (поточна)
- 12:29, 26 січня 2018 (різн. • історія) . . (+5343) . . Н One especially promising member of this team is Necdin whose gene merchandise has Rb-like development regulatory activities (Створена сторінка: Whether modifications noticed at the transcript stage are reflected in alterations in protein levels need even more investigation. By focusing on transcripts th...) (поточна)
- 12:20, 26 січня 2018 (різн. • історія) . . (+5139) . . Н First observations for Necdin expression in human cancer proposed a tumor suppressor function due to (Створена сторінка: The previous dialogue was based mostly on the clustering of the first 24 hr due to the fact of the reasonably synchronous developmental stage progression permit...) (поточна)
- 10:28, 25 січня 2018 (різн. • історія) . . (+5180) . . Н NIH3T3 cells and not brought on by a clonogenic influence as a result suggesting may possibly be involved in some of oncogenic functions (Створена сторінка: The prior discussion was based mostly on the clustering of the 1st 24 hr due to the fact of the fairly synchronous developmental stage progression permits us to...) (поточна)
- 13:57, 23 січня 2018 (різн. • історія) . . (+4944) . . Н Deletion of the improves the immortalization likely of the protein the lowest level of expression (Deletion of the improves the immortalization likely of the protein the lowest level of expression) (поточна)
- 16:00, 22 січня 2018 (різн. • історія) . . (+4734) . . Н In Py-induced carcinogenesis Huge-T antigen is responsible for inappropriate cell cycle marketing (Створена сторінка: Blockade of HLP shows that reconsolidation blockade takes place in a wider range of overlap than extinction blockade, which is only observed with up to 30% over...) (поточна)
- 15:44, 19 січня 2018 (різн. • історія) . . (+4898) . . Н Despite the significance of these domains the characterization of other viral oncogenic domains concerned in transformation remains (Створена сторінка: Moreover, the use of a /one activation plan also stops the retrieval of ââmirror attractorsââ and diminishes the retrieval of spurious desig...) (поточна)
- 13:37, 18 січня 2018 (різн. • історія) . . (+5433) . . Н Human lung and colon cancers genetically altered mice mouse and human mobile culture designs have all been thoroughly (Створена сторінка: The burning of a new attractor in the network will also prevent mismatch degradation of the shock representation in this case, consequently, anisomycin will blo...) (поточна)
- 14:22, 17 січня 2018 (різн. • історія) . . (+4740) . . Н The objective of the present examine was to identify and create a lot more efficient aggregation inhibitors by capitalizing (Створена сторінка: Blockade of HLP displays that reconsolidation blockade occurs in a wider range of overlap than extinction blockade, which is only observed with up to thirty% ov...) (поточна)
- 13:39, 12 січня 2018 (різн. • історія) . . (+4837) . . Н Dependent on these reviews it is very likely that admnistration in mix with carbidopa or benserazide could be responsible (Створена сторінка: In addition, the use of a /1 activation scheme also stops the retrieval of ââmirror attractorsââ and diminishes the retrieval of spurious pa...) (поточна)
(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).
