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PSG SE showed a significant ADAMTS12 negative correlation with the disturbance score. This finding may suggest that the subjective account of sleep disturbance is very close to similar objective sleep measurements. This may be an important finding if verified by further investigations. It would suggest that subjective accounts of sleep disturbance are less affected by biases of over and/or under reporting compared to other indices of subjective sleep parameters. A significant correlation of latency score with WASO1 in the combined group was found. This seems to indicate that sleep onset and sleep maintenance problems were usually present in the same individuals in the study sample. Polysomnographic TRT and TST showed significant negative correlations with the daytime dysfunction score. TRT and TST are reflective of the sleep duration while the daytime dysfunction score gives an account of daytime sleepiness. Liu et al,23 reported a significant relationship between short sleep duration and daytime dysfunction among Japanese Asians. The SB431542 cost significant and moderately strong negative correlation (r=-0.563, pcheck details A widely accepted approach is to maximize the sum of sensitivity and specificity (test accuracy), which is equivalent to maximization of Youden��s statistic (J=sensitivity + specificity �C 1).24 In our study, this analysis showed that a global score of >6 was the optimal cut-off point for distinguishing NS and PS in this segment of the Indian population. The cut-off score is slightly greater than that published in the presenting paper of the PSQI scale (global score >5). This again may be due to the zero sensitivity of the medicine use score in the study. Moreover, different recommendations for cut-off scores have been reported previously.8,18,22,25,26 Backhaus et al,22 concluded that a global score cut-off of 6 was better in distinguishing primary insomniacs from healthy controls in the German population. The AUC value at the experimental cut-off was 0.83 (CI 0.70�C0.93; p